Structure of PDB 1iaw Chain B Binding Site BS01

Receptor Information
>1iaw Chain B (length=304) Species: 68170 (Lentzea aerocolonigenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EPDDDLERVRATLYSLDPDGDRTAGVLRDTLDQLYDGQRTGRWNFDQLHK
TEKTHMGTLVEINLHREFQFGDGFETDYEIAGVQVDCKFSMSQGAWMLPP
ESIGHICLVIWASDQQCAWTAGLVKVIPQFLGTANRDLKRRLTPEGRAQV
VKLWPDHGKLQENLLLHIPGDVRDQIFSAKSSRGNQHGQARVNELFRRVH
GRLIGRAVIATVAQQDDFMKRVRGSGGARSILRPEGIIILGHQDNDPKVA
NDLGLPVPRKGQVVAARVVPADEGDQRQTAEIQGRRWAVAVPGDPIVEAP
VVPR
Ligand information
Receptor-Ligand Complex Structure
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PDB1iaw Structure of NaeI-DNA complex reveals dual-mode DNA recognition and complete dimer rearrangement.
Resolution2.4 Å
Binding residue
(original residue number in PDB)		Q195 G197 Q224 D225 D226 K229 R230 Q252
Binding residue
(residue number reindexed from 1)		Q186 G188 Q215 D216 D217 K220 R221 Q243
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1iaw, PDBe:1iaw, PDBj:1iaw
PDBsum1iaw
PubMed11473254
UniProtP50187|T2N1_LENAE Type II restriction enzyme NaeI (Gene Name=naeIR)

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