Structure of PDB 1hls Chain B Binding Site BS01

Receptor Information
>1hls Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALHLVCGERGFFYTPKT
Ligand information
>1hls Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1hls High-resolution structure of an engineered biologically potent insulin monomer, B16 Tyr-->His, as determined by nuclear magnetic resonance spectroscopy.
ResolutionN/A
Binding residue
(original residue number in PDB)		Q4 H5 L6 C7 L11 A14 L15 V18 C19 F24 F25 Y26 T27
Binding residue
(residue number reindexed from 1)		Q4 H5 L6 C7 L11 A14 L15 V18 C19 F24 F25 Y26 T27
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1hls, PDBe:1hls, PDBj:1hls
PDBsum1hls
PubMed8025104
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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