Structure of PDB 1hit Chain B Binding Site BS01

Receptor Information
>1hit Chain B (length=30) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FVNQHLCGSHLVEALYLVCGERGGFYTPKT
Ligand information
>1hit Chain A (length=21) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
GIVEQCCTSICSLYQLENYCN
Receptor-Ligand Complex Structure
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PDB1hit Receptor binding redefined by a structural switch in a mutant human insulin.
ResolutionN/A
Binding residue
(original residue number in PDB)
N3 Q4 H5 L6 C7 L11 L15 V18 C19
Binding residue
(residue number reindexed from 1)
N3 Q4 H5 L6 C7 L11 L15 V18 C19
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

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Molecular Function

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Cellular Component
External links
PDB RCSB:1hit, PDBe:1hit, PDBj:1hit
PDBsum1hit
PubMed1961250
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

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