Structure of PDB 1hf0 Chain B Binding Site BS01

Receptor Information
>1hf0 Chain B (length=128) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LEELEQFAKTFKQRRIKLGFTQGDVGLAMGKLYGNDFSQTTISRFEALNL
SFKNMSKLKPLLEKWLNDAERKKRTSIETNIRVALEKSFLENQKPTSEEI
TMIADQLNMEKEVIRVWFSNRRQKEKRI
Ligand information
Receptor-Ligand Complex Structure
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PDB1hf0 Differential Dimer Activities of the Transcription Factor Oct-1 by DNA-Induced Interface Swapping
Resolution2.7 Å
Binding residue
(original residue number in PDB)
D41 S43 T45 R49 N59 R102 R105 S107 K125 R153 Q154 K157
Binding residue
(residue number reindexed from 1)
D36 S38 T40 R44 N54 R71 R74 S76 K94 R122 Q123 K126
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:1hf0, PDBe:1hf0, PDBj:1hf0
PDBsum1hf0
PubMed11583619
UniProtP14859|PO2F1_HUMAN POU domain, class 2, transcription factor 1 (Gene Name=POU2F1)

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