Structure of PDB 1hcs Chain B Binding Site BS01
Receptor Information
>1hcs Chain B (length=107) Species:
9606
(Homo sapiens) [
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MDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVS
DFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCH
RLTTVCP
Ligand information
>1hcs Chain A (length=5) [
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YEEIE
Receptor-Ligand Complex Structure
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PDB
1hcs
Solution structure of the human pp60c-src SH2 domain complexed with a phosphorylated tyrosine pentapeptide.
Resolution
N/A
Binding residue
(original residue number in PDB)
R175 T179 H201 Y202 K203 T215 L237
Binding residue
(residue number reindexed from 1)
R36 T40 H62 Y63 K64 T76 L98
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:1hcs
,
PDBe:1hcs
,
PDBj:1hcs
PDBsum
1hcs
PubMed
7532003
UniProt
P12931
|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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