Structure of PDB 1hax Chain B Binding Site BS01
Receptor Information
>1hax Chain B (length=240) Species:
9823
(Sus scrofa) [
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VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRE
LTFRVVVGEHNLNQNNGTEQYVGVQKIVVHPYWNTDDVAAGYDIALLRLA
QSVTLNSYVQLGVLPRAGTILRNNSPCYITGWGLTRTNGQLAQTLQQAYL
PTVDYAICSSSSYWGSTVKNSMVCAGGDGVRSGCQGDSGGPLHCLVNGQY
AVHGVTSFVSRLGCNVTRKPTVFTRVSAYISWINNVIASN
Ligand information
>1hax Chain A (length=4) Species:
9606
(Homo sapiens) [
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VEPI
Receptor-Ligand Complex Structure
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PDB
1hax
X-Ray Snapshots of Serine Protease Catalysis Reveal a Tetrahedral Intermediate
Resolution
1.6 Å
Binding residue
(original residue number in PDB)
H57 G190 C191 Q192 G193 S195 T213 S214 F215 V216
Binding residue
(residue number reindexed from 1)
H45 G183 C184 Q185 G186 S188 T206 S207 F208 V209
Enzymatic activity
Catalytic site (original residue number in PDB)
H57 D102 Q192 G193 D194 S195 G196
Catalytic site (residue number reindexed from 1)
H45 D93 Q185 G186 D187 S188 G189
Enzyme Commision number
3.4.21.36
: pancreatic elastase.
Gene Ontology
Molecular Function
GO:0004252
serine-type endopeptidase activity
GO:0005515
protein binding
GO:0008236
serine-type peptidase activity
GO:0046872
metal ion binding
Biological Process
GO:0006508
proteolysis
Cellular Component
GO:0005576
extracellular region
GO:0005615
extracellular space
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Molecular Function
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Cellular Component
External links
PDB
RCSB:1hax
,
PDBe:1hax
,
PDBj:1hax
PDBsum
1hax
PubMed
11473259
UniProt
P00772
|CELA1_PIG Chymotrypsin-like elastase family member 1 (Gene Name=CELA1)
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