Structure of PDB 1ha5 Chain B Binding Site BS01

Receptor Information
>1ha5 Chain B (length=218) Species: 1314 (Streptococcus pyogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPDPSQLHRSSLVKNLQNIYFLYEGDPVTHENVKSVDQLLSHDLIYNVSG
PNYDKLKTELKNQEMATLFKDKNVDIYGVEYYHLCYLCENAERSACIYGG
VTNHAGNHLEIPKKIVVKVSIDGIQSLSFDIETNKKMVTAQELDYKVRKY
LTDNKQLYTNGPSKYETGYIKFIPKNKESFWFDFFPEPEFTQSKYLMIYK
DNETLDSNTSQIEVYLTT
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1ha5 Chain B Residue 3221 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1ha5 Structural Features of a Zinc Binding Site in the Superantigen Strepococcal Pyrogenic Exotoxin a (Spea1): Implications for Mhc Class II Recognition.
Resolution2.82 Å
Binding residue
(original residue number in PDB)		E2033 D2077 H2106 H2110
Binding residue
(residue number reindexed from 1)		E31 D75 H104 H108
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1ha5, PDBe:1ha5, PDBj:1ha5
PDBsum1ha5
PubMed11369867
UniProtP0DJY7|SPEA_STRPY Exotoxin type A (Gene Name=speA)

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