Structure of PDB 1h88 Chain B Binding Site BS01

Receptor Information
>1h88 Chain B (length=71) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TVDKHSDEYKIRRERNNIAVRKSRDKAKMRNLETQHKVLELTAENERLQK
KVEQLSRELSTLRNLFKQLPE
Ligand information
Receptor-Ligand Complex Structure
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PDB1h88 Mechanism of C-Myb-C/Ebpbeta Cooperation from Separated Sites on a Promoter
Resolution2.8 Å
Binding residue
(original residue number in PDB)
V285 S288 R289
Binding residue
(residue number reindexed from 1)
V20 S23 R24
Binding affinityPDBbind-CN: Kd=35.3nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:1h88, PDBe:1h88, PDBj:1h88
PDBsum1h88
PubMed11792321
UniProtP17676|CEBPB_HUMAN CCAAT/enhancer-binding protein beta (Gene Name=CEBPB)

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