Structure of PDB 1gwq Chain B Binding Site BS01

Receptor Information
>1gwq Chain B (length=242) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKKNSLALSLTADQMVSALLDAEPPILYSEFSEASMMGLLTNLADRELVH
MINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAP
NLLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNS
GVYTFLSSTLKSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQ
LLLILSHIRHMSNKGMEHLYSMKCKNVVPLYDLLLEMLDAHR
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1gwq Interaction of Transcriptional Intermediary Factor 2 Nuclear Receptor Box Peptides with the Coactivator Binding Site of Estrogen Receptor Alpha.
Resolution2.45 Å
Binding residue
(original residue number in PDB)
I358 K362 L372 V376 D538 E542 M543
Binding residue
(residue number reindexed from 1)
I52 K56 L66 V70 D232 E236 M237
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1gwq, PDBe:1gwq, PDBj:1gwq
PDBsum1gwq
PubMed11937504
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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