Structure of PDB 1g8t Chain B Binding Site BS01

Receptor Information

>1g8t Chain B (length=241) Species: 615 (Serratia marcescens)

SIDNCAVGCPTGGSSNVSIVRHAYTLNNNSTTKFANWVAYHITKDTPASG
KTRNWKTDPALNPADTLAPADYTGANAALKVDRGHQAPLASLAGVSDWES
LNYLSNITPQKSDLNQGAWARLEDQERKLIDRADISSVYTVTGPLYERDM
GKLPGTQKAHTIPSAYWKVIFINNSPAVNHYAAFLFDQNTPKGADFCQFR
VTVDEIEKRTGLIIWAGLPDDVQASLKSKPGVLPELMGCKN

Ligand information

• Ligand ID: SO4
• InChI: InChI=1S/H2O4S/c1-5(2,3)4/h(H2,1,2,3,4)/p-2
• InChIKey: QAOWNCQODCNURD-UHFFFAOYSA-L
• SMILES:
  OpenEye OEToolkits 1.5.0: [O-]S(=O)(=O)[O-]
  CACTVS 3.341: [O-][S]([O-])(=O)=O
  ACDLabs 10.04: [O-]S([O-])(=O)=O
• Formula: O4 S
• Name: SULFATE ION
• DrugBank: DB14546
• PDB chain: 1g8t Chain B Residue 802

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1g8t Atomic structure of the Serratia marcescens endonuclease at 1.1 A resolution and the enzyme reaction mechanism.
• Resolution: 1.1 Å
• Binding residue (original residue number in PDB): R57 H89
• Binding residue (residue number reindexed from 1): R53 H85
• Annotation score: 3

Enzymatic activity

• Catalytic site (original residue number in PDB): R57 H89 N110 N119 E127
• Catalytic site (residue number reindexed from 1): R53 H85 N106 N115 E123
• Enzyme Commision number: 3.1.30.2: Serratia marcescens nuclease.

Gene Ontology

Molecular Function

• GO:0003676 nucleic acid binding
• GO:0004519 endonuclease activity
• GO:0016787 hydrolase activity
• GO:0046872 metal ion binding

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:1g8t, PDBe:1g8t, PDBj:1g8t
• PDBsum: 1g8t
• PubMed: 10771425
• UniProt: P13717|NUCA_SERMA Nuclease (Gene Name=nucA)