Structure of PDB 1fzg Chain B Binding Site BS01

Receptor Information
>1fzg Chain B (length=303) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VNSNIPTNLRVLRSILENLRSKIQKLESDVSAQMEYCRTPCTVSCNIPVV
SGKECEEIIRKGGETSEMYLIQPDSSVKPYRVYCDMNTENGGWTVIQNRQ
DGSVDFGRKWDPYKQGFGNVATNTDGKNYCGLPGEYWLGNDKISQLTRMG
PTELLIEMEDWKGDKVKAHYGGFTVQNEANKYQISVNKYRGTAGNALMDG
ASQLMGENRTMTIHNGMFFSTYDRDNDGWLTSDPRKQCSKEDGGGWWYNR
CHAANPNGRYYWGGQYTWDMAKHGTDDGVVWMNWKGSWYSMRKMSMKIRP
FFP
Ligand information
Receptor-Ligand Complex Structure
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PDB1fzg Conformational changes in fragments D and double-D from human fibrin(ogen) upon binding the peptide ligand Gly-His-Arg-Pro-amide.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		N364 M367 W385 E397 D398 R406 C407 H408 D432
Binding residue
(residue number reindexed from 1)		N208 M211 W229 E241 D242 R250 C251 H252 D276
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1fzg, PDBe:1fzg, PDBj:1fzg
PDBsum1fzg
PubMed10074346
UniProtP02675|FIBB_HUMAN Fibrinogen beta chain (Gene Name=FGB)

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