Structure of PDB 1fyr Chain B Binding Site BS01
Receptor Information
>1fyr Chain B (length=98) Species:
9606
(Homo sapiens) [
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MKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGND
VQHFKVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSRNQQIFLRDIE
Ligand information
>1fyr Chain J (length=4) Species:
9606
(Homo sapiens) [
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YVNV
Receptor-Ligand Complex Structure
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PDB
1fyr
Dimer formation through domain swapping in the crystal structure of the Grb2-SH2-Ac-pYVNV complex.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
R67 R86 S88 S90 S96 Q106 H107 F108 K109 L120 W121
Binding residue
(residue number reindexed from 1)
R13 R32 S34 S36 S42 Q52 H53 F54 K55 L66 W67
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1fyr
,
PDBe:1fyr
,
PDBj:1fyr
PDBsum
1fyr
PubMed
11063574
UniProt
P62993
|GRB2_HUMAN Growth factor receptor-bound protein 2 (Gene Name=GRB2)
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