Structure of PDB 1fje Chain B Binding Site BS01

Receptor Information
>1fje Chain B (length=175) Species: 10036 (Mesocricetus auratus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSHMVEGSESTTPFNLFIGNLNPNKSVAELKVAISELFAKNDLAVVDVRT
GTNRKFGYVDFESAEDLEKALELTGLKVFGNEIKLEKPKGRDSKKVRAAR
TLLAKNLSFNITEDELKEVFEDALEIRLVSQDGKSKGIAYIEFKSEADAE
KNLEEKQGAEIDGRSVSLYYTGEKG
Ligand information
>1fje Chain A (length=22) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggccgaaaucccgaaguaggcc
<<<<..............>>>>
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1fje Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin.
ResolutionN/A
Binding residue
(original residue number in PDB)		F17 V27 R49 T52 R54 F56 Y58 K89 G90 S93 K94 K95 L103 K105 R127 L128 V129 I138 Y140
Binding residue
(residue number reindexed from 1)		F17 V27 R49 T52 R54 F56 Y58 K89 G90 S93 K94 K95 L103 K105 R127 L128 V129 I138 Y140
Binding affinityPDBbind-CN: Kd=2nM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding

View graph for
Molecular Function
External links
PDB RCSB:1fje, PDBe:1fje, PDBj:1fje
PDBsum1fje
PubMed11118222
UniProtP08199|NUCL_MESAU Nucleolin (Gene Name=NCL)

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