Structure of PDB 1fic Chain B Binding Site BS01

Receptor Information
>1fic Chain B (length=257) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGSGNGWT
VFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAI
PYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAGDAFDG
FDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMNKCHAG
HLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKIIPFNRL
GQQHHLG
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1fic Chain B Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1fic Crystal structure of a 30 kDa C-terminal fragment from the gamma chain of human fibrinogen.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		D318 D320 F322 G324
Binding residue
(residue number reindexed from 1)		D176 D178 F180 G182
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0007596 blood coagulation

View graph for
Biological Process
External links
PDB RCSB:1fic, PDBe:1fic, PDBj:1fic
PDBsum1fic
PubMed9016719
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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