Structure of PDB 1fhf Chain B Binding Site BS01

Receptor Information

>1fhf Chain B (length=304) Species: 3847 (Glycine max)

QLTPTFYRETCPNLFPIVFGVIFDASFTDPRIGASLMRLHFHDCFVQGCD
GSVLLNNTDTIESEQDALPNINSIRGLDVVNDIKTAVENSCPDTVSCADI
LAIAAEIASVLGGGPGWPVPLGRRDSLTANRTLANQNLPAPFFNLTQLKA
SFAVQGLNTLDLVTLSGGHTFGRARCSTFINRLYNFSNTGNPDPTLNTTY
LEVLRARCPQNATGDNLTNLDLSTPDQFDNRYYSNLLQLNGLLQSDQELF
STPGADTIPIVNSFSSNQNTFFSNFRVSMIKMGNIGVLTGDEGEIRLQCN
FVNG

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 1fhf Chain B Residue 501

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1fhf Structure of soybean seed coat peroxidase: a plant peroxidase with unusual stability and haem-apoprotein interactions.
• Resolution: 2.8 Å
• Binding residue (original residue number in PDB): D43 V46 G48 D50 S52
• Binding residue (residue number reindexed from 1): D43 V46 G48 D50 S52
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): R38 H42 N70 H169
• Catalytic site (residue number reindexed from 1): R38 H42 N70 H169
• Enzyme Commision number: 1.11.1.7: peroxidase.

Gene Ontology

Molecular Function

• GO:0004601 peroxidase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding
• GO:0140825 lactoperoxidase activity

Biological Process

• GO:0006979 response to oxidative stress
• GO:0042744 hydrogen peroxide catabolic process
• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0005576 extracellular region

External links

• PDB: RCSB:1fhf, PDBe:1fhf, PDBj:1fhf
• PDBsum: 1fhf
• PubMed: 11266599
• UniProt: O22443