Structure of PDB 1f5t Chain B Binding Site BS01
Receptor Information
>1f5t Chain B (length=120) Species:
1717
(Corynebacterium diphtheriae) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
KDLVDTTEMYLRTIYELEEEGVTPLRARIAERLEQSGPTVSQTVARMERD
GLVVVASDRSLQMTPTGRTLATAVMRKHRLAERLLTDIIGLDINKVHDEA
DRWEHVMSDEVERRLVKVLK
Ligand information
>1f5t Chain E (length=43) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
aacatgcaaggctaaggttagcctaaccttagccttgcatgtt
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
1f5t
Methyl groups of thymine bases are important for nucleic acid recognition by DtxR.
Resolution
3.0 Å
Binding residue
(original residue number in PDB)
T2007 Q2036 S2037 P2039 T2040 Q2043 R2047 R2050
Binding residue
(residue number reindexed from 1)
T6 Q35 S36 P38 T39 Q42 R46 R49
Binding affinity
PDBbind-CN
: Kd=460nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0003700
DNA-binding transcription factor activity
GO:0046914
transition metal ion binding
GO:0046983
protein dimerization activity
Biological Process
GO:0006355
regulation of DNA-templated transcription
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:1f5t
,
PDBe:1f5t
,
PDBj:1f5t
PDBsum
1f5t
PubMed
10956029
UniProt
P0DJL7
|DTXR_CORDI Diphtheria toxin repressor (Gene Name=dtxR)
[
Back to BioLiP
]