Structure of PDB 1ejh Chain B Binding Site BS01

Receptor Information
>1ejh Chain B (length=180) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EHYIKHPLQNRWALWFFKNDKSKTWQANLRLISKFDTVEDFWALYNHIQL
SSNLMPGCDYSLFKDGIEPMWEDEKNKRGGRWLITLNKQQRRSDLDRFWL
ETLLCLIGESFDDYSDDVCGAVVNVRAKGDKIAIWTTECENRDAVTHIGR
VYKERLGLPPKIVIGYQSHADTATKNRFVV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1ejh Cap-dependent translation initiation in eukaryotes is regulated by a molecular mimic of eIF4G.
Resolution2.2 Å
Binding residue
(original residue number in PDB)		Y34 H37 P38 Q40 V69 W73 E132 G139 E140 D143
Binding residue
(residue number reindexed from 1)		Y3 H6 P7 Q9 V38 W42 E101 G108 E109 D112
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003743 translation initiation factor activity
Biological Process
GO:0006413 translational initiation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1ejh, PDBe:1ejh, PDBj:1ejh
PDBsum1ejh
PubMed10394359
UniProtP63073|IF4E_MOUSE Eukaryotic translation initiation factor 4E (Gene Name=Eif4e)

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