Structure of PDB 1e9i Chain B Binding Site BS01

Receptor Information
>1e9i Chain B (length=430) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTGSREALEL
RDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTE
NKSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMM
NIINGGEHADNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKG
MNTAVGDEGGYAPNLGSNAEALAVIAEAVKAAGYELGKDITLAMDCAASE
FYKDGKYVLAGEGNKAFTSEEFTHFLEELTKQYPIVSIEDGLDESDWDGF
AYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKGIANSILIKFNQIGSLTE
TLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQIKTGSMSRSD
RVAKYNQLIRIEEALGEKAPYNGRKEIKGQ
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1e9i Chain B Residue 1431 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1e9i Crystal Structure of the Escherichia Coli RNA Degradosome Component Enolase
Resolution2.48 Å
Binding residue
(original residue number in PDB)		D245 E289 D316
Binding residue
(residue number reindexed from 1)		D245 E289 D316
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) S41 H158 E167 E208 D245 E289 D316 K341 H369 K392
Catalytic site (residue number reindexed from 1) S41 H158 E167 E208 D245 E289 D316 K341 H369 K392
Enzyme Commision number 4.2.1.11: phosphopyruvate hydratase.
Gene Ontology
Molecular Function
GO:0000287 magnesium ion binding
GO:0004634 phosphopyruvate hydratase activity
GO:0005515 protein binding
GO:0016829 lyase activity
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0046872 metal ion binding
Biological Process
GO:0006096 glycolytic process
GO:0006396 RNA processing
GO:0006401 RNA catabolic process
Cellular Component
GO:0000015 phosphopyruvate hydratase complex
GO:0005576 extracellular region
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0009986 cell surface
GO:0016020 membrane
GO:1990061 bacterial degradosome

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1e9i, PDBe:1e9i, PDBj:1e9i
PDBsum1e9i
PubMed11676541
UniProtP0A6P9|ENO_ECOLI Enolase (Gene Name=eno)

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