Structure of PDB 1e3m Chain B Binding Site BS01

Receptor Information
>1e3m Chain B (length=754) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQQYLRLKAQHPEILLFYRMGDFYELFYDDAKRASQLLDISLTPMAGIPY
HAVENYLAKLVNQGESVAICERKVVRIVTPGTISDEALLQERQDNLLAAI
WQDSKGFGYATLDISSGRFRLSEPADRETMAAELQRTNPAELLYAEDFAE
MSLIEGRRGLRRRPLWEFEIDTARQQLNLQFGTRDLVGFGVENAPRGLCA
AGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRNLEITQNLAGG
AENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDFTA
GLQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRAQLETVD
SAPVQALREKMGEFAELRDLLERAIIDTPPVLVRDGGVIASGYNEELDEW
RALADGATDYLERLEVRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAP
INYMRRQTLKNAERYIIPELKEYEDKVLTSKGKALALEKQLYEELFDLLL
PHLEALQQSASALAELDVLVNLAERAYTLNYTCPTFIDKPGIRITEGRHP
VVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYMRQTALIALMAYI
GSYVPAQKVEIGPIDRIFTRVGTFMVEMTETANILHNATEYSLVLMDEIG
RGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKMEGVANVH
LDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLREL
ESIS
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1e3m The Crystal Structure of DNA Mismatch Repair Protein Muts Binding to a G X T Mismatch
Resolution2.2 Å
Binding residue
(original residue number in PDB)		N468 L495 K496
Binding residue
(residue number reindexed from 1)		N432 L459 K460
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008301 DNA binding, bending
GO:0016887 ATP hydrolysis activity
GO:0030983 mismatched DNA binding
GO:0032136 adenine/cytosine mispair binding
GO:0042802 identical protein binding
GO:0043531 ADP binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0000018 regulation of DNA recombination
GO:0006281 DNA repair
GO:0006298 mismatch repair
GO:0006974 DNA damage response
Cellular Component
GO:0005829 cytosol
GO:0032300 mismatch repair complex
GO:1990710 MutS complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1e3m, PDBe:1e3m, PDBj:1e3m
PDBsum1e3m
PubMed11048711
UniProtP23909|MUTS_ECOLI DNA mismatch repair protein MutS (Gene Name=mutS)

[Back to BioLiP]