Structure of PDB 1e0e Chain B Binding Site BS01

Receptor Information
>1e0e Chain B (length=46) Species: 11720 (Human immunodeficiency virus type 2 (ISOLATE ROD)) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FLEKIEPAQEEHEKYHSNVKELSHKFGIPNLVARQIVNSCAQCQQK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1e0e Chain B Residue 147 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1e0e Refined Solution Structure of the Dimeric N-Terminal Hhcc Domain of HIV-2 Integrase
ResolutionN/A
Binding residue
(original residue number in PDB)		H12 H16 C40 C43
Binding residue
(residue number reindexed from 1)		H12 H16 C40 C43
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.47: HIV-2 retropepsin.
Gene Ontology
Molecular Function
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:1e0e, PDBe:1e0e, PDBj:1e0e
PDBsum1e0e
PubMed11101216
UniProtP04584|POL_HV2RO Gag-Pol polyprotein (Gene Name=gag-pol)

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