Structure of PDB 1dsz Chain B Binding Site BS01

Receptor Information
>1dsz Chain B (length=84) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDC
LIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQR
Ligand information
Receptor-Ligand Complex Structure
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PDB1dsz Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1.
Resolution1.7 Å
Binding residue
(original residue number in PDB)
K1245 H1246 Y1247 R1264 Q1306 E1308 R1309
Binding residue
(residue number reindexed from 1)
K18 H19 Y20 R37 Q79 E81 R82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:1dsz, PDBe:1dsz, PDBj:1dsz
PDBsum1dsz
PubMed10698945
UniProtP19793|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)

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