Structure of PDB 1dsz Chain B Binding Site BS01
Receptor Information
>1dsz Chain B (length=84) Species:
9606
(Homo sapiens) [
Search protein sequence
] [
Download receptor structure
] [
Download structure with residue number starting from 1
] [
View receptor structure
]
GSFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDC
LIDKRQRNRCQYCRYQKCLAMGMKREAVQEERQR
Ligand information
>1dsz Chain C (length=15) [
Search DNA sequence
] [
Download ligand structure
] [
Download structure with residue number starting from 1
] [
View ligand structure
]
caggtcaaaggtcag
Receptor-Ligand Complex Structure
Global view
Local view
Structure summary
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
[
Spin on
] [
Spin off
] [
Reset
]
[
High quality
] [
Low quality
]
[
White background
] [
Black background
]
PDB
1dsz
Structure of the RXR-RAR DNA-binding complex on the retinoic acid response element DR1.
Resolution
1.7 Å
Binding residue
(original residue number in PDB)
K1245 H1246 Y1247 R1264 Q1306 E1308 R1309
Binding residue
(residue number reindexed from 1)
K18 H19 Y20 R37 Q79 E81 R82
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003700
DNA-binding transcription factor activity
GO:0008270
zinc ion binding
GO:0043565
sequence-specific DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
View graph for
Molecular Function
View graph for
Biological Process
External links
PDB
RCSB:1dsz
,
PDBe:1dsz
,
PDBj:1dsz
PDBsum
1dsz
PubMed
10698945
UniProt
P19793
|RXRA_HUMAN Retinoic acid receptor RXR-alpha (Gene Name=RXRA)
[
Back to BioLiP
]