Structure of PDB 1dmy Chain B Binding Site BS01
Receptor Information
>1dmy Chain B (length=237) Species:
10090
(Mus musculus) [
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GTRQSPINIQWKDSVYDPQLAPLRVSYDAASCRYLWNTGYFFQVEFDDSC
EDSGISGGPLGNHYRLKQFHFHWGATDEWGSEHAVDGHTYPAELHLVHWN
STKYENYKKASVGENGLAVIGVFLKLGAHHQALQKLVDVLPEVRHKDTQV
AMGPFDPSCLMPACRDYWTYPGSLTTPPLAESVTWIVQKTPVEVSPSQLS
MFRTLLFSGRGEEEDVMVNNYRPLQPLRDRKLRSSFR
Ligand information
Ligand ID
ZN
InChI
InChI=1S/Zn/q+2
InChIKey
PTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0
[Zn+2]
Formula
Zn
Name
ZINC ION
ChEMBL
CHEMBL1236970
DrugBank
DB14532
ZINC
PDB chain
1dmy Chain B Residue 280 [
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Receptor-Ligand Complex Structure
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PDB
1dmy
Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design.
Resolution
2.45 Å
Binding residue
(original residue number in PDB)
H94 H96 H119
Binding residue
(residue number reindexed from 1)
H70 H72 H95
Annotation score
1
Enzymatic activity
Catalytic site (original residue number in PDB)
Y64 H94 H96 E106 H119 T199
Catalytic site (residue number reindexed from 1)
Y40 H70 H72 E82 H95 T175
Enzyme Commision number
4.2.1.1
: carbonic anhydrase.
Gene Ontology
Molecular Function
GO:0004089
carbonate dehydratase activity
GO:0008270
zinc ion binding
View graph for
Molecular Function
External links
PDB
RCSB:1dmy
,
PDBe:1dmy
,
PDBj:1dmy
PDBsum
1dmy
PubMed
7479916
UniProt
P23589
|CAH5A_MOUSE Carbonic anhydrase 5A, mitochondrial (Gene Name=Ca5a)
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