Structure of PDB 1d5x Chain B Binding Site BS01

Receptor Information
>1d5x Chain B (length=183) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDTRPRFLEQVKHECHFFNGTERVRFLDRYFYHQEEYVRFDSDVGEYRAV
TELGRPDAEYWNSQKDLLEQKRAAVDTYCRHNYGVGESFTVQRRVYPEVT
VYPAKNLLVCSVNGFYPGSIEVRWFRNGQEEKTGVVSTGLIQNGDWTFQT
LVMLETVPRSGEVYTCQVEHPSLTSPLTVEWRA
Ligand information
Receptor-Ligand Complex Structure
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PDB1d5x Peptide and peptide mimetic inhibitors of antigen presentation by HLA-DR class II MHC molecules. Design, structure-activity relationships, and X-ray crystal structures.
Resolution2.45 Å
Binding residue
(original residue number in PDB)		H13 Y30 T77 Y78 H81 N82
Binding residue
(residue number reindexed from 1)		H13 Y30 T77 Y78 H81 N82
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006955 immune response
GO:0019882 antigen processing and presentation
Cellular Component
GO:0016020 membrane
GO:0042613 MHC class II protein complex

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Biological Process
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Cellular Component
External links
PDB RCSB:1d5x, PDBe:1d5x, PDBj:1d5x
PDBsum1d5x
PubMed10841792
UniProtP01911|DRB1_HUMAN HLA class II histocompatibility antigen, DRB1 beta chain (Gene Name=HLA-DRB1)

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