Structure of PDB 1bp3 Chain B Binding Site BS01

Receptor Information
>1bp3 Chain B (length=197) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
LPPGKPEIFKCRSPNKETFTCWWRPGTDGTNYSLTYHREGETLMHECPDY
ITGGPNSCHFGKQYTSMWRTYIMMVNATNSSFSDELYVDVTYIVQPDPPL
ELAVEVKQPEDRKPYLWIKWSPPTLIDLKTGWFTLLYEIRLKPEKAAEWE
IHFAGQQTEFKILSLHPGQKYLVQVRCKPDHGYWSAWSPATFIQIPS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1bp3 Chain A Residue 500 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1bp3 The X-ray structure of a growth hormone-prolactin receptor complex.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D387 H388
Binding residue
(residue number reindexed from 1)		D180 H181
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004896 cytokine receptor activity
Cellular Component
GO:0016020 membrane

View graph for
Molecular Function
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Cellular Component
External links
PDB RCSB:1bp3, PDBe:1bp3, PDBj:1bp3
PDBsum1bp3
PubMed7984244
UniProtP16471|PRLR_HUMAN Prolactin receptor (Gene Name=PRLR)

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