Structure of PDB 1bh9 Chain B Binding Site BS01

Receptor Information
>1bh9 Chain B (length=89) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
FSEEQLNRYEMYRRSAFPKAAIKRLIQSITGTSVSQNVVIAMSGISKVFV
GEVVEEALDVCEKWGEMPPLQPKHMREAVRRLKSKGQIP
Ligand information
Ligand IDPMB
InChIInChI=1S/C6H5O3S.Hg/c7-10(8,9)6-4-2-1-3-5-6;/h2-5H,(H,7,8,9);
InChIKeyKQAOIKIZSJJTII-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1cc(ccc1S(=O)(=O)O)[Hg]
CACTVS 3.341O[S](=O)(=O)c1ccc([Hg])cc1
ACDLabs 10.04[Hg]c1ccc(cc1)S(=O)(=O)O
FormulaC6 H5 Hg O3 S
NamePARA-MERCURY-BENZENESULFONIC ACID
ChEMBL
DrugBankDB02983
ZINC
PDB chain1bh9 Chain B Residue 300 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1bh9 Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		C173 E174 E178 M179
Binding residue
(residue number reindexed from 1)		C61 E62 E66 M67
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0051123 RNA polymerase II preinitiation complex assembly
Cellular Component
GO:0005634 nucleus
GO:0005669 transcription factor TFIID complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1bh9, PDBe:1bh9, PDBj:1bh9
PDBsum1bh9
PubMed9695952
UniProtQ15544|TAF11_HUMAN Transcription initiation factor TFIID subunit 11 (Gene Name=TAF11)

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