Structure of PDB 1b72 Chain B Binding Site BS01
Receptor Information
>1b72 Chain B (length=73) Species:
9606
(Homo sapiens) [
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RKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWF
GNKRIRYKKNIGKFQEEANIYAA
Ligand information
>1b72 Chain D (length=20) [
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actctatgattgatcggctg
Receptor-Ligand Complex Structure
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PDB
1b72
Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation.
Resolution
2.35 Å
Binding residue
(original residue number in PDB)
R237 Q279 N282 N286 R290
Binding residue
(residue number reindexed from 1)
R3 Q45 N48 N52 R56
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0000981
DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677
DNA binding
Biological Process
GO:0006355
regulation of DNA-templated transcription
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Molecular Function
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Biological Process
External links
PDB
RCSB:1b72
,
PDBe:1b72
,
PDBj:1b72
PDBsum
1b72
PubMed
10052460
UniProt
P40424
|PBX1_HUMAN Pre-B-cell leukemia transcription factor 1 (Gene Name=PBX1)
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