Structure of PDB 1b72 Chain B Binding Site BS01

Receptor Information
>1b72 Chain B (length=73) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWF
GNKRIRYKKNIGKFQEEANIYAA
Ligand information
Receptor-Ligand Complex Structure
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PDB1b72 Structure of a HoxB1-Pbx1 heterodimer bound to DNA: role of the hexapeptide and a fourth homeodomain helix in complex formation.
Resolution2.35 Å
Binding residue
(original residue number in PDB)
R237 Q279 N282 N286 R290
Binding residue
(residue number reindexed from 1)
R3 Q45 N48 N52 R56
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:1b72, PDBe:1b72, PDBj:1b72
PDBsum1b72
PubMed10052460
UniProtP40424|PBX1_HUMAN Pre-B-cell leukemia transcription factor 1 (Gene Name=PBX1)

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