Structure of PDB 1ayo Chain B Binding Site BS01

Receptor Information
>1ayo Chain B (length=130) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EFPFALEVQTLPQTCDGPKAHTSFQISLSVSYIGSRPASNMAIVDVKMVS
GFIPLKPTVKMLERSNVSRTEVSNNHVLIYLDKVTNETLTLTFTVLQDIP
VRDLKPAIVKVYDYYETDEFAVAEYSAPCS
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1ayo Chain B Residue 133 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1ayo Crystal structure of the receptor-binding domain of alpha 2-macroglobulin.
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D120 E121
Binding residue
(residue number reindexed from 1)		D118 E119
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005576 extracellular region

View graph for
Cellular Component
External links
PDB RCSB:1ayo, PDBe:1ayo, PDBj:1ayo
PDBsum1ayo
PubMed9634697
UniProtQ7SIH1|A2MG_BOVIN Alpha-2-macroglobulin (Gene Name=A2M)

[Back to BioLiP]