Structure of PDB 1ar1 Chain B Binding Site BS01

Receptor Information

>1ar1 Chain B (length=252) Species: 266 (Paracoccus denitrificans)

QDVLGDLPVIGKPVNGGMNFQPASSPLAHDQQWLDHFVLYIITAVTIFVC
LLLLICIVRFNRRANPVPARFTHNTPIEVIWTLVPVLILVAIGAFSLPIL
FRSQEMPNDPDLVIKAIGHQWYWSYEYPNDGVAFDALMLEKEALADAGYS
EDEYLLATDNPVVVPVGKKVLVQVTATDVIHAWTIPAFAVKQDAVPGRIA
QLWFSVDQEGVYFGQCSELCGINHAYMPIVVKAVSQEKYEAWLAGAKEEF
AA

Ligand information

• Ligand ID: CU
• InChI: InChI=1S/Cu/q+2
• InChIKey: JPVYNHNXODAKFH-UHFFFAOYSA-N
• SMILES:
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Cu+2]
  CACTVS 3.341: [Cu++]
• Formula: Cu
• Name: COPPER (II) ION
• DrugBank: DB14552
• PDB chain: 1ar1 Chain B Residue 270

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1ar1 Structure at 2.7 A resolution of the Paracoccus denitrificans two-subunit cytochrome c oxidase complexed with an antibody FV fragment.
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): C216 C220 H224
• Binding residue (residue number reindexed from 1): C216 C220 H224
• Annotation score: 1

Enzymatic activity

• Enzyme Commision number: 7.1.1.9: cytochrome-c oxidase.

Gene Ontology

Molecular Function

• GO:0004129 cytochrome-c oxidase activity
• GO:0005507 copper ion binding
• GO:0016491 oxidoreductase activity

Biological Process

• GO:0022900 electron transport chain

Cellular Component

• GO:0016020 membrane

External links

• PDB: RCSB:1ar1, PDBe:1ar1, PDBj:1ar1
• PDBsum: 1ar1
• PubMed: 9380672
• UniProt: P08306|COX2_PARDE Cytochrome c oxidase subunit 2 (Gene Name=ctaC)