Structure of PDB 1afq Chain B Binding Site BS01

Receptor Information
>1afq Chain B (length=131) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDV
VVAGEFDQGSSSEKIQKLKIAKVFKNSKYNSLTINNDITLLKLSTAASFS
QTVSAVCLPSASDDFAAGTTCVTTGWGLTRY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1afq X-ray crystal structure of a dipeptide-chymotrypsin complex in an inhibitory interaction.
Resolution1.8 Å
Binding residue
(original residue number in PDB)		V23 S26 W27 W29 Q116 A120 C122
Binding residue
(residue number reindexed from 1)		V8 S11 W12 W14 Q101 A105 C107
Enzymatic activity
Catalytic site (original residue number in PDB) H57 D102
Catalytic site (residue number reindexed from 1) H42 D87
Enzyme Commision number 3.4.21.1: chymotrypsin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1afq, PDBe:1afq, PDBj:1afq
PDBsum1afq
PubMed9692896
UniProtP00766|CTRA_BOVIN Chymotrypsinogen A

[Back to BioLiP]