Structure of PDB 1aei Chain B Binding Site BS01

Receptor Information
>1aei Chain B (length=315) Species: 6087 (Hydra vulgaris) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VVQGTVKPHASFNSREDAETLRKAMKGIGTDEKSITHILATRSNAQRQQI
KTDYTTLFGKHLEDELKSELSGNYEAAALALLRKPDEFLAEQLHAAMKGL
GTDENALIDILCTQSNAQIHAIKAAFKLLYKEDLEKEIISETSGNFQRLL
VSMLQGGRKEDEPVNAAHAAEDAAAIYQAGEGQIGTDESRFNAVLATRSY
PQLHQIFHEYSKISNKTILQAIENEFSGDIKNGLLAIVKSVENRFAYFAE
RLHHAMKGLGTSDKTLIRILVSRSEIDLANIKETFQAMYGKSLYEFIADD
CSGDYKDLLLQITGH
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1aei Chain B Residue 317 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1aei Crystal structure of the annexin XII hexamer and implications for bilayer insertion.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		K68 L71 E76
Binding residue
(residue number reindexed from 1)		K67 L70 E75
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0005544 calcium-dependent phospholipid binding
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Cellular Component
External links
PDB RCSB:1aei, PDBe:1aei, PDBj:1aei
PDBsum1aei
PubMed7477411
UniProtP26256|ANX12_HYDVU Annexin-B12 (Gene Name=ANXB12)

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