Structure of PDB 1a1b Chain B Binding Site BS01
Receptor Information
>1a1b Chain B (length=104) Species:
9606
(Homo sapiens) [
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IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFD
NAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLT
TVCP
Ligand information
>1a1b Chain D (length=3) [
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YEc
Receptor-Ligand Complex Structure
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PDB
1a1b
Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
R158 R178 S180 E181 T182 K203 H204 Y205 K206 G239
Binding residue
(residue number reindexed from 1)
R13 R33 S35 E36 T37 K58 H59 Y60 K61 G94
Enzymatic activity
Enzyme Commision number
2.7.10.2
: non-specific protein-tyrosine kinase.
External links
PDB
RCSB:1a1b
,
PDBe:1a1b
,
PDBj:1a1b
PDBsum
1a1b
PubMed
9174343
UniProt
P12931
|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)
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