Structure of PDB 1a0n Chain B Binding Site BS01

Receptor Information
>1a0n Chain B (length=58) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWWEARSLTTGETGYI
PSNYVAPV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1a0n Structural and thermodynamic characterization of the interaction of the SH3 domain from Fyn with the proline-rich binding site on the p85 subunit of PI3-kinase.
ResolutionN/A
Binding residue
(original residue number in PDB)
Y101 Y103 W129 P144 N146 Y147
Binding residue
(residue number reindexed from 1)
Y8 Y10 W36 P51 N53 Y54
Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
External links
PDB RCSB:1a0n, PDBe:1a0n, PDBj:1a0n
PDBsum1a0n
PubMed8961927
UniProtP06241|FYN_HUMAN Tyrosine-protein kinase Fyn (Gene Name=FYN)

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