Structure of PDB 9f1c Chain As Binding Site BS01

Receptor Information

>9f1c Chain As (length=143) Species: 9986 (Oryctolagus cuniculus)

PGVTVKDVNQQEFVRALAAFLKKSGKLKVPEWVDTVKLAKHKELAPYDEN
WFYTRAASTARHLYLRGGAGVGSMTKIYGGRQRNGVMPSHFSRGSKSVAR
RVLQALEGLKMVEKDQDGGRKLTPQGQRDLDRIAGQVAAANKK

Ligand information

>9f1c Chain A2 (length=1770)

uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucguacuuggauaacugugguaa
uucuagagcuaauacaugccgacgggcgcugacccccuucgcggggggga
ugcgugcauuuaucagaucaaaaccaacccggugccggcggcuuugguga
cucuagauaaccucgggccgaucgcacgcccuccguggcggcgacgaccc
auucgaacgucugcccuaucaacuuucgaugguagucgccgugccuacca
uggugaccacgggugacggggaaucaggguucgauuccggagagggagcc
ugagaaacggcuaccacauccaaggaaggcagcaggcgcgcaaauuaccc
acucccgacccggggagguagugacgaaaaauaacaauacaggacucuuu
cgaggcccuguaauuggaaugaguccacuuuaaauccuuuaacgaggauc
cauuggagggcaagucuggugccagcagccgcgguaauuccagcuccaau
agcguauauuaaaguugcugcaguuaaaaagcucguaguuggaucuuggg
agcgggcggccgcccguccccgccucucggcgccccggggcccgaagcgu
uuacuuugaaaaaauuagaguguucaaagcaggcccgagccgccuggaua
ccgcagcuaggaauaauggaauaggaccgcgguucuauuuuguugguuuu
cggaacugaggccaugauuaagagggacggccgggggcauucguauugcg
ccgcuagaggugaaauucuuggaccggcgcaagacggaccagagcgaaag
cauuugccaagaauguuuucauuaaucaagaacgaaagucggagguucga
agacgaucagauaccgucguaguuccgaccauaaacgaugccgacuggcg
augcggcggcguuauucccaugacccgccgggcagcuuccgggaaaccaa
agucuuuggguuccggggggaguaugguugcaaagcugaaacuuaaagga
auugacggaagggcaccaccaggaguggagccugcggcuuaauuugacuc
aacacgggaaaccucacccggcccggacacggacaggauugacagauuga
uagcucuuucucgauuccgugggugguggugcauggccguucuuaguugg
uggagcgauuugucugguuaauuccgauaacgaacgagacucuggcaugc
uaacuaguuacgcgacccccgagcggucggcgucccccaacuucuuagag
ggacaaguggcguucagccacccgagauugagcaauaacaggucugugau
gcccuuagauguccggggcugcacgcgcgcuacacugacuggcucagcgu
gugccuacccuacgccggcaggcgcggguaacccguugaaccccauucgu
gauggggaucggggauugcaauuauuccccaugaacgaggaauucccagu
aagugcgggucauaagcuugcguugauuaagucccugcccuuuguacaca
ccgcccgucgcuacuaccgauuggaugguuuagugaggcccucggaucgg
ccccgccggggucggcccacggcccuggcggagcgcugagaagacggucg
aacuugacuaucuagaggaaguaaaagucguaacaagguuuccguaggug
aaccugcggaaggaucauua

...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[[[.........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<<<<....>>>>>>..
.>>>>[[..(((((.....<<<<<<<<<<<<<..>>>>.......<....
..>..)))))......]]...<<<<.<<<<......>>>>>>>>.]].]]
]...}}....]]].<<<....<<<....<<<<<<<.........>>>>>>
>>>>......>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<.
.........>>>.>>.<.<<....>>.>...]]]]]].........<<<.
...<<<<...>>>>..>>>......}}.......<<<<<<<<<.<<<...
.>>>..>>>>>>.>>>......<<..<...........>..>>.......
..<<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>.
.)))))).]]]............{{.......{{...[[[.[[....<<<
.<<<<<<<..>>>>>>>.>>><<...<<<..<<<<<>>>>>.>>>.>>..
<<<<<<.<.......<<...<.......>.<<<<.......>>>>...>>
......>.>>>..>>>........{.[[.(((((((.....>>>>>>>>>
.))))))).]].}....]]....<<<<<<..<...<<<<..<<..<<<<<
<<<...<<<......>>>......>>>>>>>>..>>.......<<....>
>...>>>>..>..>>>.>>>...]]]...}}......<<<<<<<...<..
.<<<<.<.....>.>>>>...>>>>>>>>..........<<<.<<.<<<.
.<.<<<<<<.<<<<<....>>>>>>>>>>>.>..>>>...<<..}}>>..
.>>.....>>>.....<<<......<<<<....>>>>....>>>..]]]]
..<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<........<<....
....>>..........<<<<<.<....<<<<<<.......<<.<<<....
....>>>.>>.....>>>>>>...<<.<<<..<<.<<<<<<....<<<.<
<<<<....>>>...<<<......>>>...>>.>>>....<<<...<...<
<<<..<<<<<<<<<<<<.......>>>>.>>>>.....>>>>..>>>>..
>.....<<<<<.....>>>>>........>>>....>>>.>>>.....>>
>>>>>.....>.>>>>>......>>>>.>>>.....<<.<<<........
<.......<<<.<<<<....>>>>.>>>....>.........>>>.>>..
....<.....<<<<<..........>>>>>.....>.....>>>>>....
.<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>>>.>>..
..<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<
<<<<<<<<<<<<<<.....>>>>>>>>>>>>.>.>>>>>...>>.>>>>.
.>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<..
..>>>>>>>>>.........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 9f1c NAC guides a ribosomal multienzyme complex for nascent protein processing.
• Resolution: 3.78 Å
• Binding residue (original residue number in PDB): P2 G3 K7 Q11 Q12 V15 W33 V37 K38 L39 K43 E44 L45 P47 Y48 T55 R56 S59 R62 H63 X67 G71 V72 K77 I78 G80 R82 R84 G86 V87 M88 P89 H91 F92 S96 K97 S98 R101 R102 Q105 G120 R121 Q128 R129 D132
• Binding residue (residue number reindexed from 1): P1 G2 K6 Q10 Q11 V14 W32 V36 K37 L38 K42 E43 L44 P46 Y47 T54 R55 S58 R61 H62 X66 G70 V71 K76 I77 G79 R81 R83 G85 V86 M87 P88 H90 F91 S95 K96 S97 R100 R101 Q104 G119 R120 Q127 R128 D131

External links

• PDB: RCSB:9f1c, PDBe:9f1c, PDBj:9f1c
• PDBsum: 9f1c
• PubMed: 39169182
• UniProt: G1TN62|RS19_RABIT Small ribosomal subunit protein eS19 (Gene Name=RPS19)