Structure of PDB 6th6 Chain As Binding Site BS01

Receptor Information

>6th6 Chain As (length=107) Species: 69014 (Thermococcus kodakarensis KOD1)

EIGLRVQPPAEVCNDPKCPWHGNLKIHGRYVEGIVVSDKGKKTVVVERQY
YHYLKKYERYELRKSKVHAHNPECINAKVGDKVLIAETRPISKTKSWVVV
AVLQRAE

Ligand information

>6th6 Chain Aa (length=1463)

auuccgguugauccugccggaggccacugcuauggggguccgacuaagcc
augcgagucauggggcgcgcgcgcgcaccggcggacggcucaguaacacg
ucgguaaccuacccucgggagggggauaaccccgggaaacuggggcuaau
cccccauaggccugagguacuggaagguccucaggccgaaaggggcaugc
ccgcccgaggaugggccggcggccgauuagguaguuggugggguaacggc
ccaccaagccgaagaucgguacgggccaugagagugggagcccggagaug
gacacugagacacggguccaggcccuacggggcgcagcaggcgcgaaacc
uccgcaaugcgggcaaccgcgacggggggacccccagugccguggcagcc
acggcuuuuccggaguguaaaaagcuccgggaauaagggcugggcaaggc
cgguggcagccgccgcgguaauaccggcggcccgagugguggccgcuauu
auugggccuaaagcguccguagccgggcccguaagucccuggcgaaaucc
cacggcucaaccguggggcuugcuggggauacugcgggccuugggaccgg
gagaggccggggguaccccugggguaggggugaaauccuauaaucccagg
gggaccgccaguggcgaaggcgcccggcuggaacggguccgacggugagg
gacgaaggccaggggagcgaaccggauuagauacccggguaguccuggcu
guaaaggaugcgggcuaggugucgggcgagcuucgagcucgcccggugcc
ggagggaagccguuaagcccgccgccuggggaguacggccgcaaggcuga
aacuuaaaggaauuggcgggggagcacuacaagggguggagcgugcgguu
uaauuggauucaacgccgggaaccucaccgggggcgacggcaaggccagg
cugaaggucuugccggcgagaggaggugcauggccgccgucagcucguac
cgugaggcguccacuuaagugugguaacgagcgagacccgcgcccccagu
ugccaguccuccccgcuggggaggaggcacucuggggggaccgccggcga
uaagccggaggaaggagcgggcgacgguaggucaguaugccccgaaaccc
ccgggcuacacgcgcgcuacaaugggcgggacaaugggauccgaccccga
aaggggaagggaauccccuaaacccgcccucaguucggaucgcgggcugc
aacucgcccgcgugaagcuggaaucccuaguacccgcgugucaucaucgc
gcggcgaauacgucccugcuccuugcacacaccgcccgucacuccacccg
agcgggguccgggugaggccuggucucccuucggggaggccgggucgagc
cugggcuccgugaggggggagaagucguaacaagguagccguaggggaac
cuacggcucgauc

...<<<<<.[.((((>>>>>.<<<<<<<<<..<<<<<<.<<......<<<
.<<<..<<<..<<.<<<<<..>>>>>.>>>>>......<<........<<
<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>.....
>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>.....<<<<..>>
>>.>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>
>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<
<<<............>>>>>.<<<<....>>>>...>>>>>>........
.<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<<<<<.>>>
>>>>>...<<<<<<<<.......>>>>>>>>.....<<<<<((......<
<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>......
....<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<....<<<
<<<<<.....>>>>>>>>...>>>>>>>>..>>>>>>>>>...<<<<<<.
....<<<<<<<<<..<<<<<<<<<..<<<......>>>.....>>>>>>>
>>..>>.......<<....>>.>>>>>>>....>>>.>>>...>>>...>
>>>...<<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>>
.........<<<<<<..<<<<<<<<<<<<<<.....>>>>>>>>>>>>>>
...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>..
..>>>..)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<<<<<<<<.
.....<<........>>..........<<<<<<<...<<....<<<.<<<
.......>>>.>>>..>>...<<.<<<..<<<<<<<<<....<<<<<<.<
<....>>...<<<<......>>>>..>>>>>>....<<<<<.<<<<<<<.
.<<<..<<<<<<<<...>>>>>>>>>>>...>>>>>>>.....<<<<<..
...>>>>>........>>>>>....>>>.>>>...>>>>>>>>....>>>
>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<..
..>>>>..>>....>>>.....>>>>>>>......<....<<<<<<<...
.....>>>>>>>....>.....>>>>>>.....<<<<<<<.......>>>
>>>>.......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<.
.<<<<<<<<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>..>>
>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>
>>>>>>>>.....

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6th6 Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
• Resolution: 2.55 Å
• Binding residue (original residue number in PDB): K19 I28 H29 R31 K41 K43 R50 Y52 K58 E60 R65 K66 S67 R91 P92 S94 K95 T96 K97
• Binding residue (residue number reindexed from 1): K17 I26 H27 R29 K39 K41 R48 Y50 K56 E58 R63 K64 S65 R89 P90 S92 K93 T94 K95

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6th6, PDBe:6th6, PDBj:6th6
• PDBsum: 6th6
• PubMed: 32555463
• UniProt: Q5JDH9|RS17_THEKO Small ribosomal subunit protein uS17 (Gene Name=rps17)