Structure of PDB 6skf Chain As Binding Site BS01

Receptor Information

>6skf Chain As (length=108) Species: 311400 (Thermococcus kodakarensis)

REIGLRVQPPAEVCNDPKCPWHGNLKIHGRYVEGIVVSDKGKKTVVVERQ
YYHYLKKYERYELRKSKVHAHNPECINAKVGDKVLIAETRPISKTKSWVV
VAVLQRAE

Ligand information

>6skf Chain Aa (length=1463)

auuccgguugauccugccggaggccacugcuauggggguccgacuaagcc
augcgagucauggggcgcgcgcgcgcaccggcggacggcucaguaacacg
ucgguaaccuacccucgggagggggauaaccccgggaaacuggggcuaau
cccccauaggccugagguacuggaagguccucaggccgaaaggggcaugc
ccgcccgaggaugggccggcggccgauuagguaguuggugggguaacggc
ccaccaagccgaagaucgguacgggccaugagagugggagcccggagaug
gacacugagacacggguccaggcccuacggggcgcagcaggcgcgaaacc
uccgcaaugcgggcaaccgcgacggggggacccccagugccguggcagcc
acggcuuuuccggaguguaaaaagcuccgggaauaagggcugggcaaggc
cgguggcagccgccgcgguaauaccggcggcccgagugguggccgcuauu
auugggccuaaagcguccguagccgggcccguaagucccuggcgaaaucc
cacggcucaaccguggggcuugcuggggauacugcgggccuugggaccgg
gagaggccggggguaccccugggguaggggugaaauccuauaaucccagg
gggaccgccaguggcgaaggcgcccggcuggaacggguccgacggugagg
gacgaaggccaggggagcgaaccggauuagauacccggguaguccuggcu
guaaaggaugcgggcuaggugucgggcgagcuucgagcucgcccggugcc
ggagggaagccguuaagcccgccgccuggggaguacggccgcaaggcuga
aacuuaaaggaauuggcgggggagcacuacaagggguggagcgugcgguu
uaauuggauucaacgccgggaaccucaccgggggcgacggcaaggccagg
cugaaggucuugccggcgagaggaggugcauggccgccgucagcucguac
cgugaggcguccacuuaagugugguaacgagcgagacccgcgcccccagu
ugccaguccuccccgcuggggaggaggcacucuggggggaccgccggcga
uaagccggaggaaggagcgggcgacgguaggucaguaugccccgaaaccc
ccgggcuacacgcgcgcuacaaugggcgggacaaugggauccgaccccga
aaggggaagggaauccccuaaacccgcccucaguucggaucgcgggcugc
aacucgcccgcgugaagcuggaaucccuaguacccgcgugucaucaucgc
gcggcgaauacgucccugcuccuugcacacaccgcccgucacuccacccg
agcgggguccgggugaggccuggucucccuucggggaggccgggucgagc
cugggcuccgugaggggggagaagucguaacaagguagccguaggggaac
cuacggcucgauc

...<<<<<.[.((((>>>>>.<<<<<<<<<..<<<<<<.<<......<<<
.<<<..<<<..<<.<<<<<..>>>>>.>>>>>......<<........<<
<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>.....
>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>.....<<<<..>>
>>.>>>>>>>..>>>>>>>>>.<<<....<<<...<<<<<<<.......>
>>>>>>.>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<
<<<............>>>>>.<<<<<..>>>>>...>>>>>>......<<
.<<<....<<<<....>>>>..>>>>>>>.>>>>>>..<<<<<<<<.>>>
>>>>>...<<<<<<<<.......>>>>>>>>.....<<<<<((......<
<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>......
....<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<....<<<
<<<<<.....>>>>>>>>...>>>>>>>..>>>>>>>>>>...<<<<<<.
....<<<<<<<<<..<<<<<<<<<..<<<......>>>.....>>>>>>>
>>..>>.......<<....>>.>>>>>>>....>>>.>>>...>>>...>
>>>...<<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>>
.........<<<<<<..<<<<<<<<<<<<<<.....>>>>>>>>>>>>>>
...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>..
..>>>..)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<<<<<<<<.
.....<<........>>..........<<<<<<<...<.....<<<.<<<
.......>>>.>>>...>...<<.<<<..<<<<<<<<.....<<<<<<.<
<....>>...<<<<......>>>>..>>>>>>....<<<<<.<<<<<<<.
.<<<..<<<<<<<<...>>>>>>>>>>>...>>>>>>>.....<<<<<..
...>>>>>........>>>>>.....>>.>>>...>>>>>>>>....>>>
>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<..
..>>>>..>>....>>>.....>>>>>>>......<....<<<<<<<...
.....>>>>>>>....>.....>>>>>>.....<<<<<<<.......>>>
>>>>.......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<.
.<<<<<<<<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>..>>
>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>
>>>>>>>>.....

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6skf Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
• Resolution: 2.95 Å
• Binding residue (original residue number in PDB): R2 N25 K27 H29 R31 K41 K43 K44 T45 Y52 K57 K58 E60 R65 S67 R91 P92 S94 K95 T96 K97
• Binding residue (residue number reindexed from 1): R1 N24 K26 H28 R30 K40 K42 K43 T44 Y51 K56 K57 E59 R64 S66 R90 P91 S93 K94 T95 K96

Gene Ontology

Molecular Function

• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0006412 translation

Cellular Component

• GO:0005840 ribosome
• GO:0022627 cytosolic small ribosomal subunit
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6skf, PDBe:6skf, PDBj:6skf
• PDBsum: 6skf
• PubMed: 32555463
• UniProt: Q5JDH9|RS17_THEKO Small ribosomal subunit protein uS17 (Gene Name=rps17)