Structure of PDB 8q87 Chain Ar Binding Site BS01

Receptor Information

>8q87 Chain Ar (length=144) Species: 9031 (Gallus gallus)

LVIPEKFQHILRVLNTNIDGRRKIAFAITAIKGVGRRYAHVVLRKADIDL
TKRAGELTEDEVERVITIMQNPRQYKIPDWFLNRQKDVKDGKYSQVLANG
LDNKLREDLERLKKIRAHRGLRHFWGLRVRGQHTKTTGRRGRTV

Ligand information

>8q87 Chain A2 (length=1697)

uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacacacgggcgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcuccuacuuggauaacugugguaa
uucuagagcuaauacaugccgacgagcgccgaccuccggggacgcgugca
uuuaucaguggugacucuagauaaccucgagccgaucgcacgcccccgug
gcggcgacgacccauucgaaugucugcccuaucaacuuucgaugguacug
ucugugccuaccauggugaccacggguaacggggaaucaggguucgauuc
cggagagggagccugagaaacggcuaccacauccaaggaaggcagcaggc
gcgcaaauuacccacucccgacccggggagguagugacgaaaaauaacaa
uacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaaucc
uuuaacgaggauccauuggagggcaagucuggugccagcagccgcgguaa
uuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcucgua
guuggaucuugggaucgagcugccgccugucccaggucucucggcgcccc
ggggcccgaagcguuuacuuugaaaaaauuagaguguucaaagcaggcug
gccgccggaauacuccagcuaggaauaauggaauaggacuccgguucuau
uuuguugguuuucggaaacggggccaugauuaagagggacggccgggggc
auucguauugugccgcuagaggugaaauucuuggaccggcgcaagacgaa
cuaaagcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaag
ucggagguucgaagacgaucagauaccgucguaguuccgaccauaaacga
ugccgacucgcgauccggcggcguuauucccaugacccgccgggcagcuc
ccgggaaacccaagucuuuggguuccggggggaguaugguugcaaagcug
aaacuuaaaggaauugacggaagggcaccaccaggaguggagccugcggc
uuaauuugacucaacacgggaaaccucacccggcccggacacggacagga
uugacagauugagagcucuuucucgauuccgugggugguggugcauggcc
guucuuaguugguggagcgauuugucugguuaauuccgauaacgaacgag
acucuggcaugcuaacuaguuacgcgacccccgagcggucggcguccaac
uucuuagagggacaaguggcguucagccacccgagauugagcaauaacag
gucugugaugcccuuagauguccggggcugcacgcgcgcuacacugacug
gcucagcuugugucuacccuacgccggcaggcgcggguaacccguugaac
cccauucgugauggggaucggggauugcaauuauuccccaugaacgagga
auucccaguaagugcgggucauaagcucgcguugauuaagucccugcccu
uuguacacaccgcccgucgcuacuaccgauuggaugguuuagugaggucc
ucggaucggccgucgagaagacggucgaacuugacuaucuagaggaagua
aaagucguaacaagguuuccguaggugaaccugcggaaggaucauua

...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<<<..<<....<<<<<.........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<..>>>...>>>><<.
.<<<<<...<......>..>>>>>......>>...<<<<.<<<<.....>
>>>>>>>.>>.>>>...>>>>>.>>>.<<<....<<<....<<<<<<...
........>>>>>>>>>......>>>...<<<.<<<<....>>>>....>
>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>>
.........<<<....<<<<...>>>>..>>>..>...>>.>.....<<<
<<<<<<.<<<....>>>..>>>>>>.>>>......<<..<..........
.>..>>.........<<<<<((....<.<<<<.....<<..))>>.....
..>>>>>>>>>>..>>>>>>.>>>.........<.<((.....<.<<...
<<<.<<.....<<..<<.<<....>>.>>..>>...<...<<<..<<<<<
>>>>>.>>>.>...<<<<<<.<.......<<...<.......>..<<<..
...>>>....>>......>.>>>..>>>........<.<<<<<.<<<<..
.............>>>>.>>>>>.>....>>....<<<<<<..<...<<<
<..<<..<<<<<<<<...<<<......>>>......>>>>>>>>..>>..
.....<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<
<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.........
.<<<.<<..<<..<<<<<<<<.<<<<<....>>>>>>>>>>>>>..>>..
..<<..))>>...>>.....>>>.>.>.<<<......<<<<....>>>>.
...>>>..)))).]<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<.
......<<........>>..........<<<<<.<....<<<<<<.....
..<<.<<<........>>>.>>.....>>>>>>...<<.<<<..<<.<<<
<<<....<<<.<<<<<....>>>...<<<......>>>...>>.>>>...
.<<<...<...<<<<..<<<<<<<<<<<<.......>>>>.>>>>..>>>
>..>>>>..>.....<<<<<.....>>>>>........>>>....>>>.>
>>.....>>>>>>>.....>.>>>>>....>.>>>>.>>>.....<<.<<
<........<.......<<<.<<<<....>>>>.>>>....>........
.>>>.>>......<.....<<<<<..........>>>>>.....>.....
>>>>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>
>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.
<<...<<<<...>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>
...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8q87 Structural insights into inactive ribosome complexes derived from cold-treated chick embryo cells
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): K25 F28 K34 G35 V36 G37 R38 R39 Y40 R55 W82 F83 N85 R86 Q87 K88 D110 H120 R121 R124 H125 L129 R130 V131 R132 G133 Q134 H135 T136 K137 T138 T139 G140 R141 R142 R144 T145 V146
• Binding residue (residue number reindexed from 1): K23 F26 K32 G33 V34 G35 R36 R37 Y38 R53 W80 F81 N83 R84 Q85 K86 D108 H118 R119 R122 H123 L127 R128 V129 R130 G131 Q132 H133 T134 K135 T136 T137 G138 R139 R140 R142 T143 V144

External links

• PDB: RCSB:8q87, PDBe:8q87, PDBj:8q87
• PDBsum: 8q87
• UniProt: G1TPG3|RS18_RABIT Small ribosomal subunit protein uS13 (Gene Name=RPS18)