Structure of PDB 6xyw Chain Ar Binding Site BS01

Receptor Information

>6xyw Chain Ar (length=137) Species: 3702 (Arabidopsis thaliana)

AEKVEEAEEIGYKVMGPLKPSERLFKPYEPVFAIVQIGSHQFKVSNGDSI
FTEKLKFCDINDKLELTKVLLLGSASQTIIGRPILPDATVHAVVEEHALD
EKVLIFKKKRRKNYRRTRGHRQELTKLRITDIQGIEK

Ligand information

>6xyw Chain 1 (length=2842)

gaaugcauuggauggaugcccgggcauugagaaggaaggacgcuuucaga
ggcgaaaggccauggggagauaccgucugugauccauggaucuccgaucg
ggaaaccguauccaagcuccguggcuagucugcgcucuuuggacuuugaa
aacuuagcgaacugaaacaucuaaguagcuaaaggaagggaaaucaaccg
agaccccguuaguagcggcgagcgagagcggauuugggauuuuaagaaaa
agaaagacgaagcacuucuuuuucgccagguuuacuguaauugugaaaag
guuggaagaucuggccaaagaaggugauagccccguagauucguuccuau
gguucgauccuucccaguaaaacgcggcguguucgaauucugaucgcuuu
uacgcgagaaagggggaccacccucuaagccuaaguauuccucaaugacc
gauagcguacaaguaccgugagggaaaggugaaaagaacccuaugacggg
agugcaauagagaaccugagauccgaugcgaacaaucagucgaaggagua
gucaagcgcacucacucuaacggcguaccuuuugcaugaugggucagcga
ggaaaugggaagagcggcuuaagccauuagguguaggcgcuuuccaaagg
uggaaucuucuaguucuuccuauuugacccgaaaccgaucgaucuagcca
ugagcagguugaagagagcucuaacaggccuuggaggaccgaacccacgu
auguggcaaaauacggggaugacuuguggcuaggggugaaaggccaacca
agaucggauauagcugguuuuccgcgaaaucuauuucaguagagcguaug
augucgauggcccgagguagagcacucaaugggcuaggguggcuuaccaa
ccccagggaaacuccgaauacaggccguucucguuuguacagacagacuu
uuggggugcuaagauccaaagucgagagggaaacagcccagaucguacgc
uaaggucccuaagcaaucacuuaguggaaaaggaagugaucgagcgauga
caaccaggaggugggcuuggaagcagccauccuuugaagaaagcguaaua
gcucacuggucuagcuccauggcaccgaaaauguaucagggcucaaguga
uucaccgaagcgacgagaccuugaaagcugcuuuuucaagugucaguagc
ggaacguucugucaaucggggaagguuuuuggugacaagaccuggagaua
ucagaagugagaaugcugacaugaguaacgauaaauccugugaaaaacac
gaucgccugccaguggaaggcuuucugcguucagucaaucuacgcagagu
gaaucggucccuaaggaacccccgaaagggcugccguccgauggguacac
gaaagugacgaaguugcuuugacuacaaaaccaugccucucucuuggagc
gaauuggaugaucgggccgagggcagcguagcgccucuuccccucacucu
ccuuucuccaauaugaaccuugagucaucaaaggcgagucuguuuauagu
cgcgacucuugucauagucaagaagguugaaacuuccaggaaaaaacuuc
gaauugggagggcgauccucccggugaacugaccguaccccaaaccgaca
caggugaacaaguagaguauacuagggcgcuugagagaaccaugucgaag
gaacucggcaaaaugaccccguaacuucgggagaaggggugcucuccuau
cuuuugauuaggaaagcggcacauaccaggggguagcgacuguuuauuaa
aaacacaggacucugcuaagugguaacacgauguauagagucugacaccu
gcccggugcuggaaagucaaaaggagaaguguuauaagcuuugaauggaa
gccccgguaaacggcggcaguaacucuaacuguccuaagguagcgaaauu
ccuugucgcauaaguagcgaccugcacgaaugguguaacgacugccccgc
ugucuccgacauggacccggugaaauugaauucuccgugaagaugcggag
uaccaacggcuagacgguaagaccccgugcaccuucacuauagcuucgca
gugacaaccuugaucgaauguguaggauaggugggaggucgugacauaga
aggaccaauccugaaagaccacucuuucgucuaagggugccuaaccgccg
cggcgggacacugcgagguggguaguuuaucuggggcggaugccuccuaa
agaguaacggaggugugcgaagguaggcucaagcuaagauucugcucgug
agcguaaugguauaagccugccugacugugagaccgacuggucgaacaga
gacgaaagucggccauagugauccgggagucccguguggaagggcucucg
cucaacggaucaaagguacgccggggauaacaggcugaugacucccaaga
gcucuuaucgacggagucguuuggcaccucgaugucgacucaucacaucc
ugggguugaagaaggucccaaggguucgguuguucgccgauucaaguggu
acgugaguuggguuuagaacgucgugagacaguucgguuccuaucuaccg
uugguguuaaagggagaacugcgaggagccaacccuaguacgagaggacu
ggguugggccaaccuaugguguaccgguuguuaugccaauagcagcgccg
ggcagcuaaguugguauggaagaacugcugcuuagcgggaaauccuucuc
uauacaaguucucggaacagguuuuagaacagaacuucgauaggcgggag
guggaagcaccgcgaggugugaagccaucucguacuaaacga

...<<<<<<<<<<....<<<..<<<<<<<<<<.....<<<<<<.......
.>>>.....<<<<<<<..<<.....>>.....>>>>>>>...>>>...<<
<....>>>..<<<<<<...<<<.........>>>...>>>>>>.......
..<<<<<<.....<......>......>>>>>.>...<.....<<....>
>....<<<<.....<<.....>>....>>>>....<<.............
...<<<<.........>>>>.....<<<..............<<....<<
<........>>>.<<.......((.....>>))....>.>.........>
>>..................<.<<..<..........>..>>.>......
..........<<<<<..((((>>>>>...>>....>..>.>>>>>>>.>>
...............<<....>>....>>.........<<<......>>>
...............>....>>>>>>>>>>........<<<<..<<<<<<
<<.......>>>.>>>>>..>>>>...<.<........>.>.<<<<<<..
..<<<<<<<<<<<<<.<<<...<<<....>>>...>>>............
............>>>>>>>>>>>>>..<<.<..<<<<<<<.....<<<<<
<<<<..<<<....<<<..<<.....>>..>>>.....>>>...<<<.<<<
<<........>>>>>>>>....>>>>>>>>>...<<<.....>>>.....
.>>>>>>...>..>.>>..<<<<<<....<<<<<....>>>>>.<<<<<<
<....<.<<<<<.<.....<<<...<<..<<<<...<<........>>..
.>>>>..>>..>>.>.....>.>>>>>.>.....>>>>>>.>...<<<<.
<<<<<.........>>>>>>>>>....<<<......>>>...<<<<.<<<
...<<<((......<<<<<<...........<<..<<.<<.<<<<.....
..<<<...<<...<<<<.......>>>>...>>........<<<......
>>>....>>>...>>>>.>>.>>.>>............))......>>>>
>>.>>>...>>>>>>><<<<<<<<<<<.....>>>>>>>>.>>>....>>
>>>>..<<<<<...<<<......<<.<<<<<....>>>>>.>>...>>>.
.>>>>>........>>>>>><......<<.....<<<.<<.......>>.
>>><<<<<....<<....<<...<<<<<<...<<.....>>.>>>>>>..
....<<<<<<....<<....<<<....>>>......>>....>>.....<
<<<......<<..<....<...............................
<.<<...>>...>.....................................
............>...<.<<<.....<........<<<<<<<........
>>.>>>>>.........>.....>>>>...>..>>............>>>
><..<<<<<.........>>>>>.>......>>>>..>>.....<<....
..>>...>>.<<<<.....>>>>.>>>>>..<<.<....<<<<<<<<.<<
...............<<<<<...............>>>>><<<.<<<<<<
......>.>>>>>.>>>............<<<<<<<<<..<<<.......
..>>>..<<<<<<<.....<<<....>>>.......>>>>>>>.<<<<<.
<<<..<<<<<<<...<<........<<<<<.......>>>>>........
>>.>>>>>..>>>>><<<<<<.......>>>>>>........<.......
....<<<<<.......>>>>>.....>....>>>>>..>>.>>>>>>>..
...>>.>>>>>>>>.>.>>>>.....>.....<<<<<........>>>>>
..<<<<<<<.<<<<.<<......<<<<.<<<<<<..<<<<<.<<<<<<<<
<.<.<<.<<<<<..<<<..............<<<...<............
....>.............>>>.....>>>..>>>>>.>>.>...<<<<<.
.>>>>>....>>>>>>>>>..>>>>>..<<<<.....>>>><<<<<<...
........>>>>>>..<<...<<<<<<<...<<<.........>>>....
.<..[.(((.>....>>>>>>>...<<<<..<<<<....>>>>..>>>>.
<<<....>>>.>>)))]......<<<<<<<.<<..))))..>>>>>>>>>
.............>>>>..>>>>>>.......<<<<.<.<<<<<<...<<
.......>>...>>>>>>...>>>>.>.......<<<<<..<<<<<..<<
<<<<<<<......>>>>>>..>>>.<<<<.......>>>>.....>>>>>
......>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>>>>>
>>>>.........<<<<<<...<<<<..<<<<<<<...............
>>>>>>><<<<<<...<<<<...<<<<<<<<<<<....>>>>>>..>>>>
>...>>>>.>>>>>><.<<<....<<<<<....>>>>>....>>>>>>>>
.......>>>>>>......<<<<<.......>>>>>....<<<<<<<<<<
<<....<<<<<....>>>>>...>>>.>>>>>>.>>>.....

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6xyw Cryo-EM structure of the RNA-rich plant mitochondrial ribosome.
• Resolution: 3.86 Å
• Binding residue (original residue number in PDB): R132 S148 H149 E162 K165 K211 I214 K217 K218 R219 R220 K221 N222 R224 R225 T226 R227 G228 H229 R230 Q231
• Binding residue (residue number reindexed from 1): R23 S39 H40 E53 K56 K102 I105 K108 K109 R110 R111 K112 N113 R115 R116 T117 R118 G119 H120 R121 Q122

Gene Ontology

Molecular Function

• GO:0000976 transcription cis-regulatory region binding
• GO:0003723 RNA binding
• GO:0003735 structural constituent of ribosome
• GO:0019843 rRNA binding

Biological Process

• GO:0000741 karyogamy
• GO:0006412 translation
• GO:0009553 embryo sac development
• GO:0009555 pollen development
• GO:0009567 double fertilization forming a zygote and endosperm
• GO:0010197 polar nucleus fusion

Cellular Component

• GO:0005737 cytoplasm
• GO:0005739 mitochondrion
• GO:0005840 ribosome
• GO:0005886 plasma membrane
• GO:1990904 ribonucleoprotein complex

External links

• PDB: RCSB:6xyw, PDBe:6xyw, PDBj:6xyw
• PDBsum: 6xyw
• PubMed: 32251374
• UniProt: Q8L9A0|RM21_ARATH Large ribosomal subunit protein bL21m (Gene Name=RPL21M)