Structure of PDB 6hiv Chain Ap Binding Site BS01

Receptor Information
>6hiv Chain Ap (length=261) Species: 5702 (Trypanosoma brucei brucei) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NLKGLVYPLPYYAMWRGNHNKYTYNKSTVCLWGEGDTRSMYHQHYAHAKC
PTDYGRGGREFEYLTVKRGKMLQKPLPRVQYVAEGSKPVWLFKSWHTPLS
SPSMWEREVQYAEHTPEHIGAKRPLAVVAPRTMHRYLFLMHMEKVTITVS
PLLFGYGHTIQKAVLDFYRRAISARSPFPKDKVFLFYAIDHITPRIEVTW
LDGTSYVPPVLEGASSQDLIQMVMEEAWLAADRMAAEGRVLNPLAIDDYK
WDQLVVFKKVR
Ligand information
>6hiv Chain AA (length=591) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuuuaccaauuaagaagaauauuauaauaaugggugucuuauauuuuaa
auaaauauuuaaauuccguguaguaaauuuauuauuuguauuauuuauau
aauagguguauuauauuuaaauuuuaaauuuguuguuuuauauuuagaua
cauauuuauagauuaauauauuuaaauaauauuuuaaaauuuauugaaaa
auaaauauaguaagauuauuuuaguaaauauuuauuuuucuuuguaaaua
uuauuaacuaaaauguuauauauaauaaucuaaguuaauuugaauauuaa
aaguacaaguauaauuuguaauucuaaaguauauuuauauuuuuaguagg
uaaaugaaaaguauaaauggauauaacuuaauauuuaauauuuguuuaau
gaaaaguauuuuauuauuauauuguauaguauuauuauaguguauaguuu
uuuaaaaauauaaaaaauaaaguaugaauuaauaucaaaauuuuaauaaa
aauuaaaaaauuaaaauaagaaacauuaugauauguacuauauucuuugu
auuuaauuuuuauaauuaauaagaaagaagaauauaauuua
....<<<................<<.........................
............<.....>......................>>.......
.......>>>..............<<<<........>>>><<<<......
...........<<....>>.............<<<....<<<<<<....>
>>>>>.......>>>...........<<<<<<<<..........>>>>>>
>>....<<<<............<...............<<<.......>>
>...........<<<.....>>>.......>............>>>>...
.............................>>>><.......<........
..................................................
..........<....>.......>......>.......<<<<<......>
>>>>....<<<<<<.<<<....<<<<......>>>>..<<.......>>>
>>>>>>>>.................................
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6hiv Evolutionary shift toward protein-based architecture in trypanosomal mitochondrial ribosomes.
Resolution7.8 Å
Binding residue
(original residue number in PDB)
K39 K57 Y58 R171 Y172 R206 S209 R211 Q253 K294 V296 R297
Binding residue
(residue number reindexed from 1)
K3 K21 Y22 R135 Y136 R170 S173 R175 Q217 K258 V260 R261
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit

View graph for
Cellular Component
External links
PDB RCSB:6hiv, PDBe:6hiv, PDBj:6hiv
PDBsum6hiv
PubMed30213880
UniProtQ57YA9

[Back to BioLiP]