Structure of PDB 6gaw Chain Ao Binding Site BS01

Receptor Information
>6gaw Chain Ao (length=572) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EEVVIPKKKTWDKVAILQALASTVHRDSTAAPYVFQDDPYLIPTSSVESH
SFLLAKKSGENAAKFIINSYPKYFQKDIAEPHIPCLMPEYFEPQIEDVSE
AALQERIKLQEPSANYNFQQREQSEELEEATEADNEKSKTKAGTWRTKNN
AERIFALMPEKNAHSYCTMIRGMVKHQAPTQALNLYTVLLNNRLRADVYT
FNSLIEATALVVNEKFEEKWNNILDLLKQMVTQNVKPNLQTFNTILKCLR
RFYAFGKLPALQTLREMKAIGIEPSLATYHYVIQLFYQHESPSKGSSLII
YDIMNEVMGKRFSPRDPDDDMFFQSAMRVCSSLRDLELAYQVHGLLNTGD
NWKLIGSDHRRNFYYSKFFNLLCFMEQIDVTLKWYKDLIPSVFFPHSQTM
IDLLQALDVANRLDMVPQIWKDSKEYGHTFRNELKEEILMLMARDQHPPE
LQVAFADCAADIKSTYESQPEWPASSLNYVAVLFLRAGRTQEAWKMLGLF
RKHNKIPRAELLNEFLDSAKASSSPAQAIELVKLASAFSLPVCEGLTRRV
MAEFTLTQEQREALGELTALTS
Ligand information
>6gaw Chain AA (length=960) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
acagguuugguccuggccuuucuauuaauucuuaauaaaauuacacaugc
aaguauccgcgccccggugagaaugcccuccagaucuuaaagaucaaaag
gagcagguaucaagcacaccuauaacgguagcucauaacgccuugcucaa
ccacacccccacgggaaacagcagugauaaaaauuaagccaugaacgaaa
guuugacuaaguuauauuaauuagaguugguaaaucucgugccagccacc
gcggucauacgauuaacccaaauuaauagauccacggcguaaagaguguu
uaagaaaaaaaaucacaauagaguuaaauuauaacuaagcuguaaaaagc
ccuaguuaaaauaaaauaacccacgaaagugacucuaauaauccugacac
acgauagcuaggacccaaacugggauuagauaccccacuaugccuagccc
uaaacccaaauaguuacauaacaaaacuauucgccagaguacuacucgca
acugccuaaaacucaaaggacuuggcggugcuucacauccaccuagagga
gccuguucuauaaucgauaaaccccgauagaccuuaccaacccuugccaa
uucagccuauauaccgccaucuucagcaaacccuaaaaaggaacaauagu
aagcacaaucauagcacauaaaaacguuaggucaagguguagcuuauggg
uuggaaagaaaugggcuacauuuucuacauaagaauauccaccacacgaa
aguuuuuaugaaacuaaaaaccaaaggaggauuuagcaguaaaucaagaa
uagagugcuugauugaauaaggccaugaagcacgcacacaccgcccguca
cccuccucaagcauguaguaauaaaaauaaccuauauucaauuacacaac
caugcaagaagagacaagucguaacaagguaagcauacuggaaagugugc
uuggauuacc
..((((..<<<<<<.)))).<<<<<<<<<..<<<<<<<<....<<<.<<<
..<<....>>......<<......<<<<<...<<<<<...>>>>>...>>
>.>>.<<<....<<...<<<......>>>..>>......>>>..<.....
>.>>.<<<....>>>.....>>>>>>..........<<....<<<<....
>>>>..>>...>>.>>>>>>...<.<<<<<<.....(((.....((.>>>
)).......)))..>>>.>..>>>>>>>>>.....<<<((.....<<<<.
..<<..............<<<<<<....<..<<<<<<.<<<......>>>
..>>>>>>..>...........<<....>>.>>>>>>......>>...>>
>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..
........<<<<<<<.....))..>>>>>>>.>>>.<<<........<<.
...>>......>>>..>>>>>><<<<<.<<<<<<<...<<..<<<<<..<
<<<<<<<<<.....<<........>>..........<<<<<<<.......
...<<<.<<<..<<<<<<.......<<..<<<<<....>>>.......>>
..>>......<<.....>>..........>>>...>>>>>>>>>...>>>
>>>>..>>.>>>>>>>>.....<<<<.....>>>>...........<...
.<<<<<<<......>>>>>>>....>.....>>>>>.....<<<<<<<..
.......>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.
..<<<.<<..<<<<<..<<<<<...<<<<.....>>>>..>>>>>.....
>>>>>..>>.>>>....>.>>...>.....<<<<<<<<<....>>>>>>>
>>........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB6gaw Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.
Resolution3.2 Å
Binding residue
(original residue number in PDB)
K126 Y127
Binding residue
(residue number reindexed from 1)
K72 Y73
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0019843 rRNA binding
GO:0043024 ribosomal small subunit binding
Biological Process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005739 mitochondrion

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:6gaw, PDBe:6gaw, PDBj:6gaw
PDBsum6gaw
PubMed30089917
UniProtK7GKS8

[Back to BioLiP]