Structure of PDB 6fxc Chain Ak Binding Site BS01

Receptor Information
>6fxc Chain Ak (length=114) Species: 273036 (Staphylococcus aureus RF122) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NIENGVAHIRSTFNNTIVTITDEFGNALSWSSAGALGFKGSKKSTPFAAQ
MASETASKSAMEHGLKTVEVTVKGPGPGRESAIRALQSAGLEVTAIRDVT
PVPHNGCRPPKRRR
Ligand information
>6fxc Chain Aa (length=1539) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auggagaguuugauccuggcucaggaugaacgcuggcggcgugccuaaua
caugcaagucgagcgaacggacgagaagcuugcuucucugauguuagcgg
cggacgggugaguaacacguggauaaccuaccuauaagacugggauaacu
ucgggaaaccggagcuaauaccggauaauauuuugaaccgcaugguucaa
aagugaaagacggucuugcugucacuuauagauggauccgcgcugcauua
gcuaguugguaagguaacggcuuaccaaggcaacgaugcauagccgaccu
gagagggugaucggccacacuggaacugagacacgguccagacuccuacg
ggaggcagcaguagggaaucuuccgcaaugggcgaaagccugacggagca
acgccgcgugagugaugaaggucuucggaucguaaaacucuguuauuagg
gaagaacauauguguaaguaacugugcacaucuugacgguaccuaaucag
aaagccacggcuaacuacgugccagcagccgcgguaauacguagguggca
agcguuauccggaauuauugggcguaaagcgcgcguaggcgguuuuuuaa
gucugaugugaaagcccacggcucaaccguggagggucauuggaaacugg
aaaacuugagugcagaagaggaaaguggaauuccauguguagcggugaaa
ugcgcagagauauggaggaacaccaguggcgaaggcgacuuucuggucug
uaacugacgcugaugugcgaaagcguggggaucaaacaggauuagauacc
cugguaguccacgccguaaacgaugagugcuaaguguuaggggguuuccg
ccccuuagugcugcagcuaacgcauuaagcacuccgccuggggaguacga
ccgcaagguugaaacucaaaggaauugacggggacccgcacaagcggugg
agcaugugguuuaauucgaagcaacgcgaagaaccuuaccaaaucuugac
auccuuugacaacucuagagauagagccuuccccuucgggggacaaagug
acagguggugcaugguugucgucagcucgugucgugagauguuggguuaa
gucccgcaacgagcgcaacccuuaagcuuaguugccaucauuaaguuggg
cacucuaaguugacugccggugacaaaccggaggaagguggggaugacgu
caaaucaucaugccccuuaugauuugggcuacacacgugcuacaauggac
aauacaaagggcagcgaaaccgcgaggucaagcaaaucccauaaaguugu
ucucaguucggauuguagucugcaacucgacuacaugaagcuggaaucgc
uaguaaucguagaucagcaugcuacggugaauacguucccgggucuugua
cacaccgcccgucacaccacgagaguuuguaacacccgaagccgguggag
uaaccuuuuaggagcuagccgucgaaggugggacaaaugauuggggugaa
gucguaacaagguagccguaucggaaggugcggcuggau
.....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<
<.<<<..<<<..<<.<<<<......................>>>>.>>>>
>......<<........<<<<<<<..<<...<<<<<<<.<<<<.....<<
<<<<....>>>>>>......>>>>......<<<.<...........>.>>
>.......<....<...>...>..>>>>>>>..>>>>>>>>>.<<<....
<<<..<<<<<<<<.......>>>>>>>>>>>......>>>..<<<<<<<<
....>>>>...>>>>.>>.<<<<<.<.........>>>>>>.<<<<....
>>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>>
.>>>>>>..<<<<.......<<<....>>>......>>>>....<<<<<<
.......<.<<<<<<<........>>>>>>>.>........>>>>>>...
...<<<<<(((...<<<<<.....<<.)))>>.......>>>>>>>>>>.
.>>>>>>>>>..........<<<((.....<<<<<..<<<.<<<<<<<.<
<<<<<<<<.......<<<<<<.....>>>>>>.....>>>>>>>..>>>>
>>>>>...<<<<<<<<...<<<<<<<....<<<<<<<<...<<<......
>>>......>>>>>>>>...........<<....>>.>>>>>>>..>>>>
>.>>>...>>>..>>>>>....<<<<<<<...<...<<<<.........>
>>>...>>>>>>>>..........<<<<<<..<<<<<<<<<<<<<....>
>>>>>>>>>>>>...<<..))>>.....>>>>>>.>>>.<<<......<<
<<....>>>>....>>>..)))).]<<<<<.<<<<<<<.<<..<<<<<..
<<<<<<<<<<......<<........>>..........<<<<<<<.....
..<<<<......<<<<<....>>>>>.....<<<<..>>>>....>>>.>
..<<<.<<<..<<<<<<.......<<<<<<<<<....>>>..<<<<....
..>>>>..>>>>>>.....<<<<..<.<<.........<<......>>..
.......>>>......<<<<.......>>>>........>>>>.......
..>>>...>>>>>>>>>...>>>>>>>...>>.>>>>>>>>......<<<
<<<.....<<<..<<...<<<....>>>...>>....>>>.....>>>>>
>.......<..<.<<<..<<........>>..>>>>...>.....>>>>>
.....<<<<<<<.........>>>>>>>......>>...>>>>>>>>>>.
>>....<..<<.<.<<<<.<<<..<<<<<<..<<<<....<.<<<<..<<
<..<<<...>>>.>>>.>>>>.>...>>>>..>>>>>>..>>>.>>>>..
>.>>...>.....<<<<<<<<<....>>>>>>>>>....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6fxc The cryo-EM structure of hibernating 100S ribosome dimer from pathogenic Staphylococcus aureus.
Resolution6.76 Å
Binding residue
(original residue number in PDB)
H22 R24 N28 N29 T33 N40 A41 W44 S46 G48 G54 S55 K57 P117 H118 N119 G120 R122 P124 K125 R127 R128
Binding residue
(residue number reindexed from 1)
H8 R10 N14 N15 T19 N26 A27 W30 S32 G34 G40 S41 K43 P103 H104 N105 G106 R108 P110 K111 R113 R114
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome

View graph for
Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:6fxc, PDBe:6fxc, PDBj:6fxc
PDBsum6fxc
PubMed28959035
UniProtQ2YYM1|RS11_STAAB Small ribosomal subunit protein uS11 (Gene Name=rpsK)

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