BioLiP

Receptor Information

>8oin Chain Ag (length=328) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TVDFIKKQIEEFNIGKRHLANMMGEDPETFTQEDIDRAIAYLFPSGLFEK
RARPIMKHPEEIFPKQRAIQWGEDGRPFHFLFYTGKQSYYSLMHDTYGKL
LDVEKHHNQLRAKDLLAEKTKILKDPIGSRWLIKEELEEMLVEKLSDQDY
AQFIRLLERLSALPCGATEEDFVNRFRRSIPIQSKKQLIEPLQYDEQGMA
FSRGEGKRKTAKAEVVVYGQGSGRIDVNGVDYLLYFPVTQDREQLMFPLH
FLDRLGKHDMTCAVSGGGRSAQAGAVRLAMARALCSFVTEDEVEWMRQAG
LLTADPRVRERKKPGQEGARRKFTWKKR

>8oin Chain AA (length=960) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

acagguuugguccuggccuuucuauuaauucuuaauaaaauuacacaugc
aaguauccgcgccccggugagaaugcccuccagaucuuaaagaucaaaag
gagcagguaucaagcacaccuauaacgguagcucauaacgccuugcucaa
ccacacccccacgggaaacagcagugauaaaaauuaagccaugaacgaaa
guuugacuaaguuauauuaauuagaguugguaaaucucgugccagccacc
gcggucauacgauuaacccaaauuaauagauccacggcguaaagaguguu
uaagaaaaaaaaucacaauagaguuaaauuauaacuaagcuguaaaaagc
ccuaguuaaaauaaaauaacccacgaaagugacucuaauaauccugacac
acgauagcuaggacccaaacugggauuagauaccccacuaugccuagccc
uaaacccaaauaguuacauaacaaaacuauucgccagaguacuacucgca
acugccuaaaacucaaaggacuuggcggugcuucacauccaccuagagga
gccuguucuauaaucgauaaaccccgauagaccuuaccaacccuugccaa
uucagccuauauaccgccaucuucagcaaacccuaaaaaggaacaauagu
aagcacaaucauagcacauaaaaacguuaggucaagguguagcuuauggg
uuggaaagaaaugggcuacauuuucuacauaagaauauccaccacacgaa
aguuuuuaugaaacuaaaaaccaaaggaggauuuagcaguaaaucaagaa
uagagugcuugauugaauaaggccaugaagcacgcacacaccgcccguca
cccuccucaagcauguaguaauaaaaauaaccuauauucaauuacacaac
caugcaagaagagacaagucguaacaagguaagcauacuggaaagugugc
uuggauuacc

..((((..<<<<<<.)))).<<<<<<<<<..<<<<<<<...<.<<<.<<<
..<<....>>......<<......<<<<<...<<<<<...>>>>>...>>
>.>>.<<<....<<...<<<......>>>..>>......>>>..<.....
>.>>.<<<....>>>.....>>>>>>>.........<<....<<<<....
>>>>..>>....>.>>>>>>...<.<<<<<<.....(((.....((.>>>
)).......)))..>>>.>..>>>>>>>>>.....<<<((.....<<<<.
..<<..............<<<<<<.....<.<<<<<<.<<<......>>>
..>>>>>>..>..........<<<....>>>>>>>>>......>>...>>
>>....<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>..
........<<<<<<<.....))..>>>>>>>.>>>.<<<........<<.
...>>......>>>..>>>>>><<<<<.<<<<<<<...<<..<<<<<..<
<<<<<<<<<.....<<........>>..........<<<<<<<.......
...<<<.<<<..<<<<<<.......<<..<<<<<....>>>.......>>
..>>......<<.....>>..........>>>...>>>>>>>>>...>>>
>>>>..>>.>>>>>>>>.....<<<<.....>>>>...............
.<<<<<<<......>>>>>>>..........>>>>>.....<<<<<<<..
.......>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<.
..<<<.<<..<<<<<..<<<<<...<<<<.....>>>>..>>>>>.....
>>>>>..>>.>>>....>.>>...>.....<<<<<<<<<....>>>>>>>
>>........

Receptor-Ligand Complex Structure

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PDB	8oin Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Resolution	3.6 Å
Binding residue (original residue number in PDB)	F117 E118 Q217 R277 K278 V307 G337 R338 S339 R376 R378 E379 R380 K381 K382 P383 G384 A388 R389 R390 T393 W394 K395 K396 R397
Binding residue (residue number reindexed from 1)	F48 E49 Q148 R208 K209 V238 G268 R269 S270 R307 R309 E310 R311 K312 K313 P314 G315 A319 R320 R321 T324 W325 K326 K327 R328

Enzyme Commision number

	Molecular Function
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005730	nucleolus
GO:0005739	mitochondrion
GO:0005763	mitochondrial small ribosomal subunit
GO:0005840	ribosome
GO:1990904	ribonucleoprotein complex

PDB	RCSB:8oin, PDBe:8oin, PDBj:8oin
PDBsum	8oin
PubMed	37141370
UniProt	I3LU08

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Structure of PDB 8oin Chain Ag Binding Site BS01