Structure of PDB 6skf Chain Ag Binding Site BS01

Receptor Information
>6skf Chain Ag (length=223) Species: 311400 (Thermococcus kodakarensis) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
EIAQRVLEEWEPKTKLGRLVKEGQITDIHEIFRKGYQIKEPEIVDVLLPE
VNLRENQEVLDIALTVRMTDSGRRIRFRVLAAVGNRDGYVGLGIGHGREV
GIAIRKAINYAKMNIIEIKRGCGSWECRCRRPHSIPFAVEGKEGSVRVKL
MPGPRGLGLVIGDVGKKILTLAGVQDVWSQTLGETRTTVNFAKAVFNALY
NTNRVAIKPEDIERYGIVVGRAM
Ligand information
>6skf Chain Aa (length=1463) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggaggccacugcuauggggguccgacuaagcc
augcgagucauggggcgcgcgcgcgcaccggcggacggcucaguaacacg
ucgguaaccuacccucgggagggggauaaccccgggaaacuggggcuaau
cccccauaggccugagguacuggaagguccucaggccgaaaggggcaugc
ccgcccgaggaugggccggcggccgauuagguaguuggugggguaacggc
ccaccaagccgaagaucgguacgggccaugagagugggagcccggagaug
gacacugagacacggguccaggcccuacggggcgcagcaggcgcgaaacc
uccgcaaugcgggcaaccgcgacggggggacccccagugccguggcagcc
acggcuuuuccggaguguaaaaagcuccgggaauaagggcugggcaaggc
cgguggcagccgccgcgguaauaccggcggcccgagugguggccgcuauu
auugggccuaaagcguccguagccgggcccguaagucccuggcgaaaucc
cacggcucaaccguggggcuugcuggggauacugcgggccuugggaccgg
gagaggccggggguaccccugggguaggggugaaauccuauaaucccagg
gggaccgccaguggcgaaggcgcccggcuggaacggguccgacggugagg
gacgaaggccaggggagcgaaccggauuagauacccggguaguccuggcu
guaaaggaugcgggcuaggugucgggcgagcuucgagcucgcccggugcc
ggagggaagccguuaagcccgccgccuggggaguacggccgcaaggcuga
aacuuaaaggaauuggcgggggagcacuacaagggguggagcgugcgguu
uaauuggauucaacgccgggaaccucaccgggggcgacggcaaggccagg
cugaaggucuugccggcgagaggaggugcauggccgccgucagcucguac
cgugaggcguccacuuaagugugguaacgagcgagacccgcgcccccagu
ugccaguccuccccgcuggggaggaggcacucuggggggaccgccggcga
uaagccggaggaaggagcgggcgacgguaggucaguaugccccgaaaccc
ccgggcuacacgcgcgcuacaaugggcgggacaaugggauccgaccccga
aaggggaagggaauccccuaaacccgcccucaguucggaucgcgggcugc
aacucgcccgcgugaagcuggaaucccuaguacccgcgugucaucaucgc
gcggcgaauacgucccugcuccuugcacacaccgcccgucacuccacccg
agcgggguccgggugaggccuggucucccuucggggaggccgggucgagc
cugggcuccgugaggggggagaagucguaacaagguagccguaggggaac
cuacggcucgauc
...<<<<<.[.((((>>>>>.<<<<<<<<<..<<<<<<.<<......<<<
.<<<..<<<..<<.<<<<<..>>>>>.>>>>>......<<........<<
<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>.....
>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>.....<<<<..>>
>>.>>>>>>>..>>>>>>>>>.<<<....<<<...<<<<<<<.......>
>>>>>>.>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<
<<<............>>>>>.<<<<<..>>>>>...>>>>>>......<<
.<<<....<<<<....>>>>..>>>>>>>.>>>>>>..<<<<<<<<.>>>
>>>>>...<<<<<<<<.......>>>>>>>>.....<<<<<((......<
<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>......
....<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<....<<<
<<<<<.....>>>>>>>>...>>>>>>>..>>>>>>>>>>...<<<<<<.
....<<<<<<<<<..<<<<<<<<<..<<<......>>>.....>>>>>>>
>>..>>.......<<....>>.>>>>>>>....>>>.>>>...>>>...>
>>>...<<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>>
.........<<<<<<..<<<<<<<<<<<<<<.....>>>>>>>>>>>>>>
...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>..
..>>>..)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<<<<<<<<.
.....<<........>>..........<<<<<<<...<.....<<<.<<<
.......>>>.>>>...>...<<.<<<..<<<<<<<<.....<<<<<<.<
<....>>...<<<<......>>>>..>>>>>>....<<<<<.<<<<<<<.
.<<<..<<<<<<<<...>>>>>>>>>>>...>>>>>>>.....<<<<<..
...>>>>>........>>>>>.....>>.>>>...>>>>>>>>....>>>
>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<..
..>>>>..>>....>>>.....>>>>>>>......<....<<<<<<<...
.....>>>>>>>....>.....>>>>>>.....<<<<<<<.......>>>
>>>>.......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<.
.<<<<<<<<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>..>>
>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>
>>>>>>>>.....
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6skf Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Resolution2.95 Å
Binding residue
(original residue number in PDB)		K44 T70 V71 R72 M73 D75 S76 R78 R81 R83 H101 R103 K111 K147 E148 S150 R152 V165 W183 E189 T190 R191 N195 K198
Binding residue
(residue number reindexed from 1)		K39 T65 V66 R67 M68 D70 S71 R73 R76 R78 H96 R98 K106 K142 E143 S145 R147 V160 W178 E184 T185 R186 N190 K193
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6skf, PDBe:6skf, PDBj:6skf
PDBsum6skf
PubMed32555463
UniProtQ5JJG8|RS5_THEKO Small ribosomal subunit protein uS5 (Gene Name=rps5)

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