Structure of PDB 6th6 Chain Ae Binding Site BS01

Receptor Information
>6th6 Chain Ae (length=174) Species: 69014 (Thermococcus kodakarensis KOD1) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDPKRQRKKYETPSHPWIKERLDRERVLKRNYALKNKKELWRHETQLKEF
RRRARRLLAARGKQAEIERQQLLQRLYRLGLLPADAVLDDVLSLTVEDVL
ERRLQTIVYRKGLARTMKQARQLIVHGHIEVNGQVIRSPGYLVLREEEDT
ITYAKGSPFAKEGHPERMVIEQAK
Ligand information
>6th6 Chain Aa (length=1463) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auuccgguugauccugccggaggccacugcuauggggguccgacuaagcc
augcgagucauggggcgcgcgcgcgcaccggcggacggcucaguaacacg
ucgguaaccuacccucgggagggggauaaccccgggaaacuggggcuaau
cccccauaggccugagguacuggaagguccucaggccgaaaggggcaugc
ccgcccgaggaugggccggcggccgauuagguaguuggugggguaacggc
ccaccaagccgaagaucgguacgggccaugagagugggagcccggagaug
gacacugagacacggguccaggcccuacggggcgcagcaggcgcgaaacc
uccgcaaugcgggcaaccgcgacggggggacccccagugccguggcagcc
acggcuuuuccggaguguaaaaagcuccgggaauaagggcugggcaaggc
cgguggcagccgccgcgguaauaccggcggcccgagugguggccgcuauu
auugggccuaaagcguccguagccgggcccguaagucccuggcgaaaucc
cacggcucaaccguggggcuugcuggggauacugcgggccuugggaccgg
gagaggccggggguaccccugggguaggggugaaauccuauaaucccagg
gggaccgccaguggcgaaggcgcccggcuggaacggguccgacggugagg
gacgaaggccaggggagcgaaccggauuagauacccggguaguccuggcu
guaaaggaugcgggcuaggugucgggcgagcuucgagcucgcccggugcc
ggagggaagccguuaagcccgccgccuggggaguacggccgcaaggcuga
aacuuaaaggaauuggcgggggagcacuacaagggguggagcgugcgguu
uaauuggauucaacgccgggaaccucaccgggggcgacggcaaggccagg
cugaaggucuugccggcgagaggaggugcauggccgccgucagcucguac
cgugaggcguccacuuaagugugguaacgagcgagacccgcgcccccagu
ugccaguccuccccgcuggggaggaggcacucuggggggaccgccggcga
uaagccggaggaaggagcgggcgacgguaggucaguaugccccgaaaccc
ccgggcuacacgcgcgcuacaaugggcgggacaaugggauccgaccccga
aaggggaagggaauccccuaaacccgcccucaguucggaucgcgggcugc
aacucgcccgcgugaagcuggaaucccuaguacccgcgugucaucaucgc
gcggcgaauacgucccugcuccuugcacacaccgcccgucacuccacccg
agcgggguccgggugaggccuggucucccuucggggaggccgggucgagc
cugggcuccgugaggggggagaagucguaacaagguagccguaggggaac
cuacggcucgauc
...<<<<<.[.((((>>>>>.<<<<<<<<<..<<<<<<.<<......<<<
.<<<..<<<..<<.<<<<<..>>>>>.>>>>>......<<........<<
<<<<<..<<...<<<<<<<.<<<<<....<<<<<......>>>>>.....
>>>>>...<<<<<<<<<.<<......>>>>>>>>>>>.....<<<<..>>
>>.>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<<<.......>
>>>>>>>>>>......>>>..<<<<<<<<....>>>>...>>>>.>>.<<
<<<............>>>>>.<<<<....>>>>...>>>>>>........
.<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<<<<<<<.>>>
>>>>>...<<<<<<<<.......>>>>>>>>.....<<<<<((......<
<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>>>>......
....<<<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<....<<<
<<<<<.....>>>>>>>>...>>>>>>>>..>>>>>>>>>...<<<<<<.
....<<<<<<<<<..<<<<<<<<<..<<<......>>>.....>>>>>>>
>>..>>.......<<....>>.>>>>>>>....>>>.>>>...>>>...>
>>>...<<<<<<<...<<...<<<<.<.....>.>>>>...>>>>>>>>>
.........<<<<<<..<<<<<<<<<<<<<<.....>>>>>>>>>>>>>>
...<<..))>>.....>>>>>>.>>>.<<<......<<<<....>>>>..
..>>>..)))).]<<<<<.<<<<<<<..<<.<<<<<<..<<<<<<<<<<.
.....<<........>>..........<<<<<<<...<<....<<<.<<<
.......>>>.>>>..>>...<<.<<<..<<<<<<<<<....<<<<<<.<
<....>>...<<<<......>>>>..>>>>>>....<<<<<.<<<<<<<.
.<<<..<<<<<<<<...>>>>>>>>>>>...>>>>>>>.....<<<<<..
...>>>>>........>>>>>....>>>.>>>...>>>>>>>>....>>>
>>>>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<..
..>>>>..>>....>>>.....>>>>>>>......<....<<<<<<<...
.....>>>>>>>....>.....>>>>>>.....<<<<<<<.......>>>
>>>>.......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<.
.<<<<<<<<<<<<<..<<<<<<<<<<<<<....>>>>>>>>>>>>>..>>
>>>>>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>
>>>>>>>>.....
Receptor-Ligand Complex Structure
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PDB6th6 Dynamic RNA acetylation revealed by quantitative cross-evolutionary mapping.
Resolution2.55 Å
Binding residue
(original residue number in PDB)		G2 D3 P4 K5 Q7 R8 K9 S15 H16 P17 W18 K36 N37 K38 K39 R43 R54 Q65 Q72 R79 R116 T117 R122 Q123 V126 H127 H129 Q135 I137 S139 H165 E167
Binding residue
(residue number reindexed from 1)		G1 D2 P3 K4 Q6 R7 K8 S14 H15 P16 W17 K35 N36 K37 K38 R42 R53 Q64 Q71 R78 R115 T116 R121 Q122 V125 H126 H128 Q134 I136 S138 H164 E166
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
GO:0042274 ribosomal small subunit biogenesis
Cellular Component
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0043226 organelle
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6th6, PDBe:6th6, PDBj:6th6
PDBsum6th6
PubMed32555463
UniProtQ5JJF2|RS4_THEKO Small ribosomal subunit protein uS4 (Gene Name=rps4)

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