Structure of PDB 8q87 Chain Ad Binding Site BS01

Receptor Information

>8q87 Chain Ad (length=262) Species: 9031 (Gallus gallus)

ARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNR
LKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIEKTGEHFRL
VYDTKGRFAVHRITAEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPD
PLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERH
PGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEE
RDKRLAAKQSSG

Ligand information

>8q87 Chain A2 (length=1697)

uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacacacgggcgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcuccuacuuggauaacugugguaa
uucuagagcuaauacaugccgacgagcgccgaccuccggggacgcgugca
uuuaucaguggugacucuagauaaccucgagccgaucgcacgcccccgug
gcggcgacgacccauucgaaugucugcccuaucaacuuucgaugguacug
ucugugccuaccauggugaccacggguaacggggaaucaggguucgauuc
cggagagggagccugagaaacggcuaccacauccaaggaaggcagcaggc
gcgcaaauuacccacucccgacccggggagguagugacgaaaaauaacaa
uacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaaucc
uuuaacgaggauccauuggagggcaagucuggugccagcagccgcgguaa
uuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcucgua
guuggaucuugggaucgagcugccgccugucccaggucucucggcgcccc
ggggcccgaagcguuuacuuugaaaaaauuagaguguucaaagcaggcug
gccgccggaauacuccagcuaggaauaauggaauaggacuccgguucuau
uuuguugguuuucggaaacggggccaugauuaagagggacggccgggggc
auucguauugugccgcuagaggugaaauucuuggaccggcgcaagacgaa
cuaaagcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaag
ucggagguucgaagacgaucagauaccgucguaguuccgaccauaaacga
ugccgacucgcgauccggcggcguuauucccaugacccgccgggcagcuc
ccgggaaacccaagucuuuggguuccggggggaguaugguugcaaagcug
aaacuuaaaggaauugacggaagggcaccaccaggaguggagccugcggc
uuaauuugacucaacacgggaaaccucacccggcccggacacggacagga
uugacagauugagagcucuuucucgauuccgugggugguggugcauggcc
guucuuaguugguggagcgauuugucugguuaauuccgauaacgaacgag
acucuggcaugcuaacuaguuacgcgacccccgagcggucggcguccaac
uucuuagagggacaaguggcguucagccacccgagauugagcaauaacag
gucugugaugcccuuagauguccggggcugcacgcgcgcuacacugacug
gcucagcuugugucuacccuacgccggcaggcgcggguaacccguugaac
cccauucgugauggggaucggggauugcaauuauuccccaugaacgagga
auucccaguaagugcgggucauaagcucgcguugauuaagucccugcccu
uuguacacaccgcccgucgcuacuaccgauuggaugguuuagugaggucc
ucggaucggccgucgagaagacggucgaacuugacuaucuagaggaagua
aaagucguaacaagguuuccguaggugaaccugcggaaggaucauua

...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<<<..<<....<<<<<.........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<..>>>...>>>><<.
.<<<<<...<......>..>>>>>......>>...<<<<.<<<<.....>
>>>>>>>.>>.>>>...>>>>>.>>>.<<<....<<<....<<<<<<...
........>>>>>>>>>......>>>...<<<.<<<<....>>>>....>
>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>>
.........<<<....<<<<...>>>>..>>>..>...>>.>.....<<<
<<<<<<.<<<....>>>..>>>>>>.>>>......<<..<..........
.>..>>.........<<<<<((....<.<<<<.....<<..))>>.....
..>>>>>>>>>>..>>>>>>.>>>.........<.<((.....<.<<...
<<<.<<.....<<..<<.<<....>>.>>..>>...<...<<<..<<<<<
>>>>>.>>>.>...<<<<<<.<.......<<...<.......>..<<<..
...>>>....>>......>.>>>..>>>........<.<<<<<.<<<<..
.............>>>>.>>>>>.>....>>....<<<<<<..<...<<<
<..<<..<<<<<<<<...<<<......>>>......>>>>>>>>..>>..
.....<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<
<<<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>.........
.<<<.<<..<<..<<<<<<<<.<<<<<....>>>>>>>>>>>>>..>>..
..<<..))>>...>>.....>>>.>.>.<<<......<<<<....>>>>.
...>>>..)))).]<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<.
......<<........>>..........<<<<<.<....<<<<<<.....
..<<.<<<........>>>.>>.....>>>>>>...<<.<<<..<<.<<<
<<<....<<<.<<<<<....>>>...<<<......>>>...>>.>>>...
.<<<...<...<<<<..<<<<<<<<<<<<.......>>>>.>>>>..>>>
>..>>>>..>.....<<<<<.....>>>>>........>>>....>>>.>
>>.....>>>>>>>.....>.>>>>>....>.>>>>.>>>.....<<.<<
<........<.......<<<.<<<<....>>>>.>>>....>........
.>>>.>>......<.....<<<<<..........>>>>>.....>.....
>>>>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>
>>>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.
<<...<<<<...>>>>...>>.>>>>..>>>.>>>>>>>>...>>.>>>>
...>.>>...>.....<<<<<<<<<<..>>>>>>>>>>.........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8q87 Structural insights into inactive ribosome complexes derived from cold-treated chick embryo cells
• Resolution: 2.4 Å
• Binding residue (original residue number in PDB): A2 R3 G4 P5 K6 K7 H8 K10 R11 V12 K16 M19 D21 K22 F27 A28 P29 R30 T33 G34 K37 L38 R49 T57 G58 K62 M66 K75 R77 K106 R108 K128 V131 G132 T133 K134 G135 V140 A144 T146 R148 K155 G186 A187 R200 H201 P202 G203 R240 I248
• Binding residue (residue number reindexed from 1): A1 R2 G3 P4 K5 K6 H7 K9 R10 V11 K15 M18 D20 K21 F26 A27 P28 R29 T32 G33 K36 L37 R48 T56 G57 K61 M65 K74 R76 K105 R107 K127 V130 G131 T132 K133 G134 V139 A143 T145 R147 K154 G185 A186 R199 H200 P201 G202 R239 I247

External links

• PDB: RCSB:8q87, PDBe:8q87, PDBj:8q87
• PDBsum: 8q87
• UniProt: P47836|RS4_CHICK Small ribosomal subunit protein eS4 (Gene Name=RPS4)