Structure of PDB 8q7z Chain Ad Binding Site BS01

Receptor Information

>8q7z Chain Ad (length=262) Species: 9031 (Gallus gallus)

ARGPKKHLKRVAAPKHWMLDKLTGVFAPRPSTGPHKLRECLPLIIFLRNR
LKYALTGDEVKKICMQRFIKIDGKVRTDITYPAGFMDVISIEKTGEHFRL
VYDTKGRFAVHRITAEEAKYKLCKVRKIFVGTKGIPHLVTHDARTIRYPD
PLIKVNDTIQIDLETGKITDFIKFDTGNLCMVTGGANLGRIGVITNRERH
PGSFDVVHVKDANGNSFATRLSNIFVIGKGNKPWISLPRGKGIRLTIAEE
RDKRLAAKQSSG

Ligand information

>8q7z Chain A2 (length=1676)

uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacacacgggcgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcuccuacuuggauaacugugguaa
uucuagagcuaauacaugccgacgagcgccgaccuccggggacgcgugca
uuuaucaguggugacucuagauaaccucgagccgaucgcacgcccccgug
gcggcgacgacccauucgaaugucugcccuaucaacuuucgaugguacug
ucugugccuaccauggugaccacggguaacggggaaucaggguucgauuc
cggagagggagccugagaaacggcuaccacauccaaggaaggcagcaggc
gcgcaaauuacccacucccgacccggggagguagugacgaaaaauaacaa
uacaggacucuuucgaggcccuguaauuggaaugaguccacuuuaaaucc
uuuaacgaggauccauuggagggcaagucuggugccagcagccgcgguaa
uuccagcuccaauagcguauauuaaaguugcugcaguuaaaaagcucgua
guuggaucuugggauucccaguuuacuuugaaaaaauuagaguguucaaa
gcaggcuggccgccggaauacuccagcuaggaauaauggaauaggacucc
gguucuauuucggaaacggggccaugauuaagagggacggccgggggcau
ucguauugugccgcuagaggugaaauucuuggaccggcgcaagacgaacu
aaagcgaaagcauuugccaagaauguuuucauuaaucaagaacgaaaguc
ggagguucgaagacgaucagauaccgucguaguuccgaccauaaacgaug
ccgacucgcgauccggcggcguuauucccaugacccgccgggcagcuccc
gggaaacccaagucuuuggguuccggggggaguaugguugcaaagcugaa
acuuaaaggaauugacggaagggcaccaccaggaguggagccugcggcuu
aauuugacucaacacgggaaaccucacccggcccggacacggacaggauu
gacagauugagagcucuuucucgauuccgugggugguggugcauggccgu
ucuuaguugguggagcgauuugucugguuaauuccgauaacgaacgagac
ucuggcaugcuaacuaguuacgcgacccccgagcggucggcguccaacuu
cuuagagggacaaguggcguucagccacccgagauugagcaauaacaggu
cugugaugcccuuagauguccggggcugcacgcgcgcuacacugacuggc
ucagcuugugucuacccuacgccggcaggcgcggguaacccguugaaccc
cauucgugauggggaucggggauugcaauuauuccccaugaacgaggaau
ucccaguaagugcgggucauaagcucgcguugauuaagucccugcccuuu
guacacaccgcccgucgcuacuaccgauuggaugguuuagugagguccuc
ggaucggccccggcggggucggccacggcccugccggagcgucgagaaga
cggucgaacuugacuaucuagaggaaguaaaagucguaacaagguuuccg
uaggugaaccugcggaaggaucauua

...<<<<<.[.((((>>>>><<<.<<<<<<...<.<<..<......<<<.
<<<..<<....<<....<<..........>>...>>.>>......<<...
.....<<<.<<<..<<....<<<<<.........<<.....<<.<<<...
..>>>.>>......>>.........<<<<...<<<..>>>...>>>><<.
.<<<<<...<......>..>>>>>......>>...<<<<.<<<<.....>
>>>>>>>.>>.>>>...>>>>>.>>>.<<<....<<<....<<<<<<...
........>>>>>>>>>......>>>...<<<.<<<<....>>>>....>
>>.>>.<<.<<<..........>>>.>>.<.<<....>>.>...>>>>>>
.........<<<....<<<<...>>>>..>>>..>...>>.>.....<<<
<<<<<<.<<<....>>>..>>>>>>.>>>......<<..<..........
.>..>>.........<<<<<((......<<<<.....<<..))>>.....
..>>>>.>>>>>..>>>>>>.>>>.........<.<((.....<.<<...
<<<.<<...<.<<....>>>..<<<<<<.<.......<<...<.......
>..<<<.....>>>....>>......>.>>>..>>>........<.<<<<
<.<<<<.....>>>>.>>>>>.>....>>....<<<<<<..<...<<<<.
.<<..<<<<<<<<...<<<......>>>......>>>>>>>>..>>....
...<<....>>...>>>>..>..>>>.>>>...>>>...>>.>....<<<
<<<<...<...<<<<.<.....>.>>>>...>>>>>>>>..........<
<<.<<..<<..<<<<<<<<.<<<<<....>>>>>>>>>>>>>..>>....
<<..))>>...>>.....>>>.>.>.<<<......<<<<....>>>>...
.>>>..)))).]<<<<<.<<<<<<<..<<..<<<<<..<<<.<<<<<<..
....<<........>>..........<<<<<.<....<<<<<<.......
<<.<<<........>>>.>>.....>>>>>>...<<.<<<..<<.<<<<<
<....<<<.<<<<<....>>>...<<<......>>>...>>.>>>....<
<<...<...<<<<..<<<<<<<<<<<<.......>>>>.>>>>..>>>>.
.>>>>..>.....<<<<<.....>>>>>........>>>....>>>.>>>
.....>>>>>>>.....>.>>>>>...>>.>>>>.>>>.....<<.<<<.
.......<.......<<<.<<<<....>>>>.>>>....>.........>
>>.>>......<.....<<<<<..........>>>>>.....>.....>>
>>>.....<<<<<<<<.......>>>>>>>>......>>...>>>>>>>>
>>.>>....<..<<.<..<<<<.<<....<<<<<<<<.<<<..<<<<.<<
...<<<<<.<<<<<<..<<<<....>>>>..>>>>>>...>>>>>...>>
.>>>>..>>>.>>>>>>>>...>>.>>>>...>.>>...>.....<<<<<
<<<<<..>>>>>>>>>>.........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 8q7z Structural insights into inactive ribosome complexes derived from cold-treated chick embryo cells
• Resolution: 2.5 Å
• Binding residue (original residue number in PDB): A2 R3 G4 P5 K6 K7 H8 K10 V12 K16 M19 D21 K22 T24 F27 P29 R30 T33 G34 K37 R49 T57 G58 K62 M66 K75 R77 K106 R108 K128 V131 G132 T133 K134 G135 V140 A144 T146 R148 K155 G186 A187 H201 P202 G203 R221 I248
• Binding residue (residue number reindexed from 1): A1 R2 G3 P4 K5 K6 H7 K9 V11 K15 M18 D20 K21 T23 F26 P28 R29 T32 G33 K36 R48 T56 G57 K61 M65 K74 R76 K105 R107 K127 V130 G131 T132 K133 G134 V139 A143 T145 R147 K154 G185 A186 H200 P201 G202 R220 I247

External links

• PDB: RCSB:8q7z, PDBe:8q7z, PDBj:8q7z
• PDBsum: 8q7z
• UniProt: P47836|RS4_CHICK Small ribosomal subunit protein eS4 (Gene Name=RPS4)