Structure of PDB 4v6x Chain Ad Binding Site BS01

Receptor Information
>4v6x Chain Ad (length=53) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QQLYWSHPRKFGQGSRSCRVCSNRHGLIRKYGLNMCRQCFRQYAKDIGFI
KLD
Ligand information
>4v6x Chain B2 (length=1861) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uaccugguugauccugccaguagcauaugcuugucucaaagauuaagcca
ugcaugucuaaguacgcacggccgguacagugaaacugcgaauggcucau
uaaaucaguuaugguuccuuuggucgcucgcuccucucccacuuggauaa
cugugguaauucuagagcuaauacaugccgacgggcgcugacccccuucg
cgggggggaugcgugcauuuaucagaucaaaaccaacccggucagccccu
cuccggccccggccggggggcgggcgccggcggcuuuggugacucuagau
aaccucgggccgaucgcacgccccccguggcggcgacgacccauucgaac
gucugcccuaucaacuuucgaugguagucgccgugccuaccauggugacc
acgggugacggggaaucaggguucgauuccggagagggagccugagaaac
ggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccacucccga
cccggggagguagugacgaaaaauaacaauacaggacucuuucgaggccc
uguaauuggaaugaguccacuuuaaauccuuuaacgaggauccauuggag
ggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguaua
uuaaaguugcugcaguuaaaaagcucguaguuggaucuugggagcgggcg
ggcgguccgcgagccaccgcccguccccgccccuugccucucggcgcccc
cucgaugcucuuagcugagugucccgcggggcccgaagcguuuacuuuga
aaaaauuagaguguucaaagcaggcccgagccgccuggauaccgcagcua
ggaauaauggaauaggaccgcgguucuauuuuguugguuuucggaacuga
ggccaugauuaagagggacggccgggggcauucguauugcgccgcuagag
gugaaauucuuggaccggcgcaagacggaccagagcgaaagcauuugcca
agaauguuuucauuaaucaagaacgaaagucggagguucgaagacgauca
gauaccgucguaguuccgaccauaaacgaugccgaccggcgaugcggcgg
cguuauucccaugacccgccgggcagcuuccgggaaaccaaagucuuugg
guuccggggggaguaugguugcaaagcugaaacuuaaaggaauugacgga
agggcaccaccaggaguggagccugcggcuuaauuugacucaacacggga
aaccucacccggcccggacacggacaggauugacagauugauagcucuuu
cucgauuccgugggugguggugcauggccguucuuaguugguggagcgau
uugucugguuaauuccgauaacgaacgagacucuggcaugcuaacuaguu
acgcgacccccgagcggucggcgucccccaacuucuuagagggacaagug
gcguucagccacccgagauugagcaauaacaggucugugaugcccuuaga
uguccggggcugcacgcgcgcuacacugacuggcucagcgugugccuacc
cuacgccggcaggcgcggguaacccguugaaccccauucgugauggggau
cggggauugcaauuauuccccaugaacgaggaauucccaguaagugcggg
ucauaagcuugcguugauuaagucccugcccuuuguacacaccgcccguc
gcuacuaccgauuggaugguuuagugaggcccucggaucggccccgccgg
ggucggcccacggcccuggcggagcgcugagaagacggucgaacuugacu
aucuagaggaaguaaaagucguaacaagguuuccguaggugaaccugcgg
aaggaucauua
...<<<<<...[[[[>>>>>[[[.((((((.....{{.........[[[.
[[[..<<....<<....<<..........>>...>>.>>......{{...
.....[[[......{{....[[[....................<<.....
<<.<<<.....>>>.>>......>>.........<<<<...<<<<<<...
.>>>>>>...>>>>[[..(((((.....<<<<<<<<<<<<.<..<<<<<<
<<<<<<<....>>>>>>>>>.>>>>....>>>>..............)))
))......]]...<<<<.<<<<......>>>>>>>>....]]]...}}..
..]]].<<<....<<<....<<<<<<<.........>>>>>>>>>>....
..>>>...<<<.<<<<....>>>>....>>>.}}.<<.<<<.........
.>>>.>>.<.<<....>>.>...]]]]]].........<<<....<<<..
...>>>..>>>......}}.......<<<<<<<<<.<<<....>>>.>.>
>>>>.>>>......<<..<...........>..>>.........<<<<<(
(......<<<<.....<<..))>>.......>>>>.>>>>>..)))))).
]]]............{{.......{{...[[[.[[....<<<.<.<<<<<
<<<<<<.<<>>....>>>>>>>>>>>.>.>>>...<<...<<<..<<<<<
...<<<<<<<......>>>>>>>....>>>>>.>>>.>>..<<<<<..<.
......<<...<.......>.<<<<.......>>>>...>>......>..
>>..>>>.......[[....(((((((.....>>>>>>>>>.))))))).
..]]....]]....<<<<<<..<...<<<<..<<..<<<<<<<<...<<<
......>>>......>>>>>>>.>.>>.......<<....>>...>>>>.
.>..>>>.>>>...]]]...}}......<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<<..<.<<<<<<
.<<<<......>>>>>>>>>>.>..>>>...<<..}}>>...>>.....>
>>.....<<<......<<<......>>>....>>>..]]]]..<<<<<.<
<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>...
.......<<<<<......<<<<<<.......<<.<<<........>>>.>
>.....>>>>>>.<.<<.<<<..<<<<<<<<<....<<<.<<<<<....>
>>...<<<......>>>...>>.>>>....<<<...<...<<<<..<<<<
....<<<..<<<<....>>>>.>>>....>>>>..>>>>..>.....<<<
<<.....>>>>>........>>>....>>>.>>>...>.>>>>>>>>...
...>>>>>...>>.>>>>.>>>.....<<.<<<........<.......<
<<.<<<<....>>>>.>>>....>.........>>>.>>...........
.<<<<<..........>>>>>...........>>>>>.....<<<<<<<<
.......>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<
..<<<<.<<....<<<<<<<<.<<<..<<<<.<<...<<<<<.<<<<<<<
<<<<<.....>>>>>>>>>>>>...>>>>>...>>.>>>>..>>>.>>>>
>>>>...>>.>>>>...>.>>...>.....<<<<<<<<<....>>>>>>>
>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v6x Structures of the human and Drosophila 80S ribosome.
Resolution5.0 Å
Binding residue
(original residue number in PDB)		W8 S9 H10 P11 R12 K13 F14 G15 Q16 R19 R22 N26 R27 H28 G29 R32 K33 Y34 R40 Q41 R44 Q45 L55 D56
Binding residue
(residue number reindexed from 1)		W5 S6 H7 P8 R9 K10 F11 G12 Q13 R16 R19 N23 R24 H25 G26 R29 K30 Y31 R37 Q38 R41 Q42 L52 D53
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0005925 focal adhesion
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:0070062 extracellular exosome
GO:0098556 cytoplasmic side of rough endoplasmic reticulum membrane
GO:1990904 ribonucleoprotein complex

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4v6x, PDBe:4v6x, PDBj:4v6x
PDBsum4v6x
PubMed23636399
UniProtP62273|RS29_HUMAN Small ribosomal subunit protein uS14 (Gene Name=RPS29)

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