Structure of PDB 4v6w Chain Ad Binding Site BS01

Receptor Information
>4v6w Chain Ad (length=52) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TLWYSHPRKYGQGSRCCRACSNRHGLIRKYGLNICRQCFREYANDIGFKK
LD
Ligand information
>4v6w Chain B2 (length=1957) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auucugguugauccugccaguaguuauaugcuugucucaaagauuaagcc
augcaugucuaaguacacacgaauuaaaagugaaaccgcaaaaggcucau
uauaucaguuaugguuccuuagaucguuaacaguuacuuggauaacugug
guaauucuagagcuaauacaugcaauuaaaacaugaaccuuaugggacgu
gugcuuuuauuaggcuaaaaccaagcgaucgcaagaucguuauauugguu
gaacucuagauaacaugcagaucguauggucuuguaccgacgacagaucu
uucaaaugucugcccuaucaacuuuugaugguaguaucuaggacuaccau
gguugcaacggguaacggggaaucaggguucgauuccggagagggagccu
gagaaacggcuaccacaucuaaggaaggcagcaggcgcguaaauuaccca
cucccagcucggggagguagugacgaaaaauaacaauacaggacucauau
ccgaggcccuguaauuggaaugaguacacuuuaaauccuuuaacaaggac
caauuggagggcaagucuggugccagcagccgcgguaauuccagcuccaa
uagcguauauuaaaguuguugcgguuaaaacguucguaguugaacuugug
cuucauacggguaguauacuauaccuuuauguauguaagcguauuaccgg
uggaguucuuauaugugaucauauguuccuccuauuuaaaaaccugcauu
agugcucuuaaacgaguguuauugugggccgguacuauuacuuugaacaa
auuagagugcuuaaagcaggcuucaaaugccugaauauucugugcauggg
auaaugaaauaagaccucuguucugcuuucauugguuuucagaucaagag
guaaugauuaauagaagcaguuugggggcauuaguauuacgacgcgagag
gugaaauucuuggaccgucguaagacuaacuuaagcgaaagcauuugcca
aagauguuuucauuaaucaagaacgaaaguuagagguucgaaggcgauca
gauaccgcccuaguucuaaccauaaacgaugccagcuagcaauugggugu
agcuacuuuuauggcucucucagucgcuuccgggaaaccaaagcuuuuug
ggcuccgggggaaguaugguugcaaagcugaaacuuaaaggaauugacgg
aagggcaccaccaggaguggagccugcggcuuaauuugacucaacacggg
aaaacuuaccaggucgaacauaaguguguaagacagauugauagcucuuu
cucgaaucuaugggugguggugcauggccguucuuaguucguggagugau
uugucugguuaauuccgauaacgaacgagacucaaauauauuaaauagau
aucuucaggauuauggugcugaagcuuauguagccuucauucauguuggc
aguaaaaugcuuauuguguuugaauguguuuauguaaguggagccguacc
uguugguuugucccauuauaaggacacuagcuucuuaaauggacaaauug
cgucuagcaauaaugagauugagcaauaacaggucugugaugcccuuaga
uguccugggcugcacgcgcgcuacaaugaaaguaucaacguguauuuccu
agaccgagagguccggguaaaccgcugaaccacuuucaugcuugggauug
ugaacugaaacuguucacgaugaacuuggaauucccaguaagugugaguc
auuaacucgcauugauuacgucccugcccuuuguacacaccgcccgucgc
uacuaccgauugaauuauuuagugaggucuccggacgugaucacugugac
gccuugcguguuacgguuguuucgcaaaaguugaccgaacuugauuauuu
agaggaaguaaaagucguaacaagguuuccguaggugaaccugcggaagg
aucauua
...<<<<<...[[[[>>>>>[[[[.((((((................{{{
.{{{..<<....<<....<<.........>>...>>.>>...........
.....{{{.{{{..{{....[[[[..............<<.....<<.<<
<.....>>>.>>......>>..........<<<<<............>>>
>>[[..(((((.....<<<<<<<<.<<<<<....>>>>>...........
........)))))...]]...<<<<.<<<<.....>>>>>>>>...]]]]
...}}}}}.}}}.<<<....<<<....<<<<<<<<.......>>>>>>>>
>>>......>>>...<<<.<<<<....>>>>....>>>....<<.<<<..
........>>>.>>.<.<<....>>.>...}}}}}}.........<<<..
..<<<.....>>>..>>>...............<<<<<<<<<.<<<....
..>>>..>>>>>>.>>>...<..<<<.<...........>>.>>>.....
...<<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>
..))))))]]]].........{{{{{.....[[[[...[[[.[[.....<
<<<.<<<<.<<<<<<<>>>>..>>.>....>>>>..>>>>....<<<<<<
.<<<<.....<<<<<<<<>>>>>>>>..>>>>..........<<<<<<.<
<<<<<<<......>>>>>>>>.>>>>>>>>>>>>..<<<<<<.<<.....
..<<...<.......>..<<<.......>>>....>>.......>>.>>.
.>>>>........((((((.(..(.......>>>>>>>>...)..)))))
)).....]]....<<<<..<<<<...<<<<..<<<.<<<<<<<<.<.<<<
......>>>.....>>>>>>>>>.>>>.......<<....>>...>>>>.
.>>>>.>.>>>...]]]...]]]]....<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<<..<<<<<.<.
.<<<<......>>>>.>.>>>>>..>>>...<<..}}>>...>>......
>>>.}}}.<<<......<<<<....>>>>....>>>..]]]]..<<<<<.
<<<<<<<..<<..<<<<<..<<<.<<<<<<......<<........>>..
........<<<<<.<...<<<<........<<<.<<<........>>>.>
>>......>>>>...<<.<<<..<<.<<<<<<....<<<<<<<<<....>
>>...<<<......>>>...>>>>>>....<<<<<.<<..<<<<..<<..
<<<..<<<<..<<<<<<......<<<<<<<<<<<.<<<<..<<<<<.<<<
<......>>>>.>>.>>>..>>>>...>.>>>>>>>>>>...>>>>>>>>
>>..>>>..<<<<........>>>>.....>>..>>>>.>>.....<<<<
<.....>>>>>.......>>>>>....>>>.>>>.....>>>>>>>....
.>.>>>>>...>>.>>>>.>>>.....<<<<<<........<.....<<<
.<<<<....>>>>.>>>....>.........>>>>>>.............
...<..........>...............>>>>>.....<<<<<<<<..
.....>>>>>>>>......>>...>>>>>>>>>>.>>....<..<<.<..
<<<<.<<....<<<<.<<<.<<<..<<<<..<.....<<<.<<<<<<<<<
<.<....>>>>>>>>>.>>..>>>.....>..>>>>..>>>.>>>.>>>>
...>>.>>>>...>.>>...>.....<<<<<<<<<....>>>>>>>>>..
.......
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4v6w Structures of the human and Drosophila 80S ribosome.
Resolution6.0 Å
Binding residue
(original residue number in PDB)
W7 Y8 S9 H10 R12 Y14 G15 Q16 R19 C24 N26 R27 H28 G29 L30 R32 K33 Y34 R40 Q41 R44 E45 D56
Binding residue
(residue number reindexed from 1)
W3 Y4 S5 H6 R8 Y10 G11 Q12 R15 C20 N22 R23 H24 G25 L26 R28 K29 Y30 R36 Q37 R40 E41 D52
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:4v6w, PDBe:4v6w, PDBj:4v6w
PDBsum4v6w
PubMed23636399
UniProtQ9VH69|RS29_DROME Small ribosomal subunit protein uS14 (Gene Name=RpS29)

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