Structure of PDB 4bts Chain AY Binding Site BS01

Receptor Information
>4bts Chain AY (length=228) Species: 5911 (Tetrahymena thermophila) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MKFNISYPLTGAQKCIEIDDDKKCNIFMDKKMGQEVEGDTLGDEFKGYVF
KIAGGNDKDGFPMKQGVMVRGRVRLLLSEGHSCFTSRRSGFRKRKSVRGC
IVGPDMRVLALQIVKKGVAEIDGLTTVTLPRKLGPKRANNIKKLFGLKKE
DDPILIKKSVIRRTFKTAKGKDRTKCPKIQRLITPERILRKKVYKAEKTQ
RYVKTNAAKEEYEKFLSEWKKQRAAKAH
Ligand information
>4bts Chain AA (length=1717) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
aaccugguugauccugccaguuacauaugcuugucuuaaauauuaaccca
ugcaugugccaguucaguauugaacagcgaaacugcgaauggcucauuaa
aacaguuauaguuuauuugauaauuaaagauuacauggauaaccgagcua
auuguugggcuaauacaugcuuaaaauuccguguccugcgaccggaacgu
auuuauuagauauuagaccaaucgcagcaaugugauugagaugaaucaaa
guaacugaucggaucgagguuuaccucgauaaaucaucuaaguuucugcc
cuaucagcucucgaugguaguguauuggacuaccauggcagucacgggua
acggagaauuaggguucgauuccggagaaggagccugagaaacggcuacu
acaacuacgguucggcagcagggaagaaaauuggccaauccuaauucagg
gagccagugacaagaaauagcaagcugggaaacuuacguuucuacggcau
ugaaaugagaacaguguaaaucucuuagcgaggaacaauuggagggcaag
ucauggugccagcagccgcgguaauuccagcuccaauagcguauauuaaa
guuguugcaguuaaaaagcucguaguugaacuucuguucagguucauuuc
gauucgucgugugaaacuggacauacguuugcguaaacauuuuacuguga
aaaaauuagaguguuccaggcagguuuuagcccgaauacauuagcaugga
auaauggaauaggacuaaguccauuuuauugguucuuggauuugguaaug
auuaauagggacaguugggggcauuaguauuuaauagucagaggugaaau
ucuuggauuuauuaaggacuaacuaaugcgaaagcauuugccaaagaugu
uuucauuaaucaagaacgaaaguuaggggaucaaagacgaucagauaccg
ucguagucuuaacuauaaacuauaccgacucgggaucggcuggaauaaau
guccagucggcaccguaugagaaaucaaagucuuuggguucugggggaag
uaugguacgcaagucugaaacuuaaaggaauugacggaacagcacaccag
aaguggaaccugcggcuuaauuugacucaacacggggaaacucacgagcg
caagacagagaagggauugacagauugagagcucuuucuugauucuuugg
gugguggugcauggccguucuuaguugguggagugauuugucugguuaau
uccguuaacgaacgagaccuuaaccugcuaacuagucugcuuguaaauaa
cagguuguacuucuuagagggacuauugugcaauaagccaauggaaguuu
aaggcaauaacaggucugugaugccccuagacgugcucggccgcacgcgc
guuacaaugacuggcgcaaaaaguauuuccuguccugggaagguacgggu
aaucuuauuaauaccagucguguuagggauaguucuuuggaauuguggau
cuugaacgaggaauuucuaguaagugcaagucaucagcuugcguugauua
ugucccugccguuuguacacaccgcccgucgcuuguaguaacgaaugguc
uggugaaccuucuggacugcgacagcaauguugcggaaaaauaaguaaac
ccuaccauuuggaacaacaagaagucguaacaagguaucuguaggugaac
cugcagauggaucauua
...<<<<<.{.[[[[>>>>><.<.<<<<<<...<<<<.........<<<.
<<<..<<....<<...<<........>>...>>.>>......<<..<...
..<<<..<<..<<....<<<<..............<<.....<<.<<<..
...>>>.>>......>>.........<<<<<.<<<....>>>>>>>>.<.
..<<<<<........((((((..<<<....>>>......<......>..>
>>>>.....>...<<<<<<....>>>>>>...>>>>...>>>>..>>>.<
<<....<<<....<<<<<<<<.......>>>>>>>>>>>......>>>..
.<<<<<<<<....>>>>...>>>>>>>.<<.<<<..........>>>.>>
..<<<....>>>.....>>>>>>.........<<<....<<<.....>>>
..>>>......>>>>.....<<<<<<<.<.<<<....>>>>...>>>>.>
>>..........<<.........>>.............<<<<<((.....
...<<<.....<<..))>>.......>>>..>>>>>..>>>>>>.>.>..
.......<<<[[.....<.<<...<<<.<<....<<<<<<<.<<<<<..<
<<<..>>>>.>>>>>.>>>>>>>...<<<<<..>>>>>...<<<<<<<<.
......<<...<.......>..<<<....>>>....>>......>>>>>.
.>>>.........<<<<<<<<<<.....))))))..>>>>>>>>>>....
.>>....<<<<<<.<<...<<<<..<<..<<<<<<<<...<<<......>
>>......>>>>>>>>..>>.......<<....>>...>>>>...>>>>>
.>>>...>>>...>>.>...<<<<<<<<...<...<<<<.........>>
>>...>>>>>>>>>.........<<<.<<.<<<..<<<<<<<<<......
.>>>>>>>>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<...
...<<.<<....>>>>....>>>..]]]].}<<<<<.<<<.<<<.<<.<<
<<<<..<<<.<<<<<.......<<........>>..........<<<<<<
<....<<<<<<.......<<.<<<........>>>.>>.....>>>>>>.
..<<.<<<..<<<<<<<<<....<<<.<<<<<....>>>...<<<.....
.>>>...>>.>>>....<<<<<.<<..<<<<..<<<..<<<<<<.....>
>>>>>...>>>..>>>>.>>....<<<<.<<.....>>>>>>.......>
>>>>....>>>.>>>...>.>>>>>>>.....>>>>>>>....>.>>>>.
>>>.....<<<<<<.......<<.....<<<<<<<<....>>>.>>>>>.
...>>........>>>>>>...........<<.<<<..........>>>.
>>..........>>>>>>....<<<<<<<<.......>>>>>>>>.....
.>>...>>>.>>>>>>.>>....<..<<.<.<<<<<.<<..<<<<<<<<.
.<<<..<<.<..<...<<<<<<<<....>>>>>>>>...>..>.>>..>>
>..>>>>>>>>..>>.>>>>>..>.>>...>.....<<<<<<<<<....>
>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB4bts The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A.
Resolution3.703 Å
Binding residue
(original residue number in PDB)		K2 N4 P8 Q13 C15 K31 N56 D59 G60 F61 P62 Q65 G66 R72 R74 H81 S82 C83 F84 T85 R87 R88 S89 G90 R92 K93 R94 K95 S96 R107 V108 Q112 R131 K132 L133 G134 K136 R137 N139 N140 K143 K149 K157 R162 T167 K169 K171 R173 T174 K175 C176 P177 K178 I179 Q180 R181 I183 R187 I188 R190 K191 Y194 K195 K198 R201 Y202 T205 K220 R223
Binding residue
(residue number reindexed from 1)		K2 N4 P8 Q13 C15 K31 N56 D59 G60 F61 P62 Q65 G66 R72 R74 H81 S82 C83 F84 T85 R87 R88 S89 G90 R92 K93 R94 K95 S96 R107 V108 Q112 R131 K132 L133 G134 K136 R137 N139 N140 K143 K149 K157 R162 T167 K169 K171 R173 T174 K175 C176 P177 K178 I179 Q180 R181 I183 R187 I188 R190 K191 Y194 K195 K198 R201 Y202 T205 K220 R223
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:4bts, PDBe:4bts, PDBj:4bts
PDBsum4bts
PubMed23851459
UniProtE6PBS4

[Back to BioLiP]