Structure of PDB 6xu8 Chain AX Binding Site BS01

Receptor Information
>6xu8 Chain AX (length=143) Species: 7227 (Drosophila melanogaster) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MGKPRGLRTARKHVNHRRDQRWADKDYKKAHLGTRWKANPFGGASHAKGI
VLEKVGVEAKQPNSAIRKCVRVQLIKNGKKITAFVPRDGSLNYIEENDEV
LVAGFGRKGHAVGDIPGVRFKVVKVANVSLLALYKEKKERPRS
Ligand information
>6xu8 Chain B2 (length=1936) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auucugguugauccugccaguaguuauaugcuugucucaaagauuaagcc
augcaugucuaaguacacacgaauuaaaagugaaaccgcaaaaggcucau
uauaucaguuaugguuccuuagaucguuaacaguuacuuggauaacugug
guaauucuagagcuaauacaugcaauuaaaacaugaaccuuaugggacgu
gugcuuuuauuaggcuaaaaccaagcgaucgcaagaucguuauauugguu
gaacucuagauaacaugcagaucguauggucuuguaccgacgacagaucu
uucaaaugucugcccuaucaacuuuugaugguaguaucuaggacuaccau
gguugcaacggguaacggggaaucaggguucgauuccggagagggagccu
gagaaacggcuaccacaucuaaggaaggcagcaggcgcguaaauuaccca
cucccagcucggggagguagugacgaaaaauaacaauacaggacucauau
ccgaggcccuguaauuggaaugaguacacuuuaaauccuuuaacaaggac
caauuggagggcaagucuggugccagcagccgcgguaauuccagcuccaa
uagcguauauuaaaguuguugcgguuaaaacguucguaguugaacuugug
cuucauacggguaguauacuauaccuuuauguauguaagcguauuaccgg
uggaguucuuauaugugaucauauguuccuccuauuuaaaaaccugcauu
agugcucuuaaacgaguguuauugugggccgguacuauuacuuugaacaa
auuagagugcuuaaagcaggcuucaaaugccugaauauucugugcauggg
auaaugaaauaagaccucuguucugcuuucauugguuuucagaucaagag
guaaugauuaauagaagcaguuugggggcauuaguauuacgacgcgagag
gugaaauucuuggaccgucguaagacuaacuuaagcgaaagcauuugcca
aagauguuuucauuaaucaagaacgaaaguuagagguucgaaggcgauca
gauaccgcccuaguucuaaccauaaacgaugccagcuagcaauugggugu
agcuacuuuuauggcucucucagucgcuuccgggaaaccaaagcuuuuug
ggcuccgggggaaguaugguugcaaagcugaaacuuaaaggaauugacgg
aagggcaccaccaggaguggagccugcggcuuaauuugacucaacacggg
aaaacuuaccaggucgaacauaaguguguaagacagauugauagcucuuu
cucgaaucuaugggugguggugcauggccguucuuaguucguggagugau
uugucugguuaauuccgauaacgaacgagacucaaauauauuaaauagau
aucuucaggauuauggugcugaagcuuauguagccuucauuauuguguuu
gaauguguuuauguaaguggagccguaccuguugguuugucccauuauaa
ggacacuagcuucuuaaauggacaaauugcgucuagcaauaaugagauug
agcaauaacaggucugugaugcccuuagauguccugggcugcacgcgcgc
uacaaugaaaguaucaacguguauuuccuagaccgagagguccggguaaa
ccgcugaaccacuuucaugcuugggauugugaacugaaacuguucacgau
gaacuuggaauucccaguaagugugagucauuaacucgcauugauuacgu
cccugcccuuuguacacaccgcccgucgcuacuaccgauugaauuauuua
gugaggucuccggacgugaucacugugacgccuugcguguuacgguuguu
ucgcaaaaguugaccgaacuugauuauuuagaggaaguaaaagucguaac
aagguuuccguaggugaaccugcggaaggaucauua
...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<<..<......<<<
.<<<..<<....<<....<<.........>>...>>.>>......<<...
.....<<<.<<<..<<....<<<<..............<<.....<<.<<
<.....>>>.>>......>>...........<<<<............>>>
>.<<..<<<<<.....(((...((..<<<<....>>>>........<...
.....>..>>>>>...>>...<...................>....>>>>
...>>>>>.>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>
>>>......>>>...<<<.<<<<....>>>>....>>>.>>.<<.<<<..
........>>>.>>.<.<<....>>.>...>>>>>>.........<<<..
..<<<.....>>>..>>>..>...>>.>.....<.<<<<<...<<<....
..>>>....>>>>..>.>.....<<.................>>......
...<<<<<((......<<<<.....<<..))>>.......>>>>.>>>>>
..>>>>>>>>>>.........<<<[[.....<<<<...<<<.<<.....<
<<<...<<......................>>....>>>>......<<..
..................................................
..............................>>....<<<<<<.<<.....
..<<...<.......>..<<<.......>>>....>>.......>>.>>.
.>>>>..........................))...)))...........
.......>>....<<<<..<.<<...<<<<..<<..<<<<<<<<...<<<
......>>>......>>>>>>>.>.>>.......<<....>>...>>>>.
..>>>.>.>>>...>>>...>>>>....<<<<<<<...<...<<<<.<..
...>.>>>>...>>>>>>>>..........<<<.<<.<<<.<<<<<<...
.<<<........>>>...>>>>>>.>>>...<<..]]>>...>>......
>>>.>>>.<<<......<<<......>>>....>>>..)))).}<<....
<<<<<<<..<<..<<<<<.<<<<.<<<<<<......<<........>>..
........<<<<......................<<<........>>>..
...............<<.<<<...<.<<<<<.....<<<.<.........
.....................>.>>>....<<<<..<<..<.<.......
.<.........<..<...................................
.......................>..>.......>...<<<<........
>>>>..........>.>.>>............................>>
>>.....>>.>>>.....>.>>>>>........>>>>...>>.>>>>.>>
>.>...<<<<<<..............<<<.<<<<....>>>>.>>>....
..........>>>>>>.........<<.....<..........>....>>
.........>>>>>.....<<<<<<<<.......>>>>>>>>......>>
...>>>>>>>....>>....<..<<.<..<<<<.<<....<<<<.<<<.<
<<..<<<<..<....<<<<.<<....<<<.........>>>.....>>..
>>>>....>..>>>>..>>>.>>>.>>>>...>>.>>>>...>.>>...>
.....<<<<<<<<<....>>>>>>>>>.........
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB6xu8 Ribosome heterogeneity in Drosophila melanogaster gonads through paralog-switching.
Resolution3.0 Å
Binding residue
(original residue number in PDB)		M1 G2 K3 P4 R5 G6 L7 R8 T9 R11 K12 H13 R17 R18 Q20 A23 D24 K25 W36 K37 A44 S45 H46 K48 K60 Q61 N63 S64 K68 P86 R87 D88 G104 R107 K108 V112 G113 D114 R119 K124 S129 K137
Binding residue
(residue number reindexed from 1)		M1 G2 K3 P4 R5 G6 L7 R8 T9 R11 K12 H13 R17 R18 Q20 A23 D24 K25 W36 K37 A44 S45 H46 K48 K60 Q61 N63 S64 K68 P86 R87 D88 G104 R107 K108 V112 G113 D114 R119 K124 S129 K137
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0002181 cytoplasmic translation
GO:0006412 translation
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005791 rough endoplasmic reticulum
GO:0005829 cytosol
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:0022626 cytosolic ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6xu8, PDBe:6xu8, PDBj:6xu8
PDBsum6xu8
PubMed34283226
UniProtQ8T3U2|RS23_DROME Small ribosomal subunit protein uS12 (Gene Name=RpS23)

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