Structure of PDB 6nu3 Chain AX Binding Site BS01

Receptor Information
>6nu3 Chain AX (length=316) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TNENDPAKHGDQHEGQHYNISPQDLETVFPHGLPPRFVMQVKTFSEACLM
VRKPALELLHYLKNTSFAYPAIRYLLYGEKGTGKTLSLCHVIHFCAKQDW
LILHIPDAHLWVKNCRDLRFDQPLEASTWLKNFKTTNSPLGEVVEQGITR
VRNATDAVGIVLKELKRQSSLGMFHLLVAVDGINALWGRTTLKREDKSPI
APEELALVHNLRKMMKNDWHGGAIVSALSQTGSLFKPRKAYLPQELLGKE
GFDALDPFIPILVSNYNPKEFESCIQYYLENNWLQHEKAPTEEGKKELLF
LSNANPSLLERHCAYL
Ligand information
>6nu3 Chain AA (length=923) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
auagguuugguccuagccuuucuauuagcucuuaguaagauuacacaugc
aagcauccccguuccagugaguucacccucuaaaucgaucaaaaggaaca
agcaucaagcacgcagcaaugcagcucaaaacgcuuagccuagccacacc
cccacgggaaacagcagugauuaaccuuuagcaauaaacgaaaguuuaac
uaagcuauacuaaccccaggguuggucaauuucgugccagccaccgcggu
cacacgauuaacccaagucaauagaccggcguaaagaguguuuuagauca
caauaaagcuaaaacucaccugaguuguaaaaaacuccaguugacacaaa
auagacuacgaaaguggcuuuaacauaucugaacacacaauagcuaagac
ccaaacugggauuagauaccccacuaugcuuagcccuaaaccucaacagu
ucaacaaaacugcucgccagaacacuacgagccacagcuuaaaacucaaa
ggaccuggcggugcuucauaucccucuagaggagccuguucuguaaucga
uaaaccccgaucaaccucaccaccucuugcucagccuauauaccgccauc
uucagcaaacccugaugaaggcuacaaaguaagcgcaaguacccacguaa
agacguuaggucaagguguagcccaugagguggcaagaaaugggcuacau
uuucuaccccagaaacgauagcccuuaugaaauaagggucgaagguggau
uuagcaguaaacuaagaguagagugcuuaguugaacagggcccugaagcg
cguacacaccgcccgucacccuccucaaguauacuucaaaggacuuaacu
aaaaccccuacgcauuuauauagaggagacgucguaacaugguaagugua
cuggaaagugcacuuggacgaac
..((((..<<<<<<.)))).<<<<<<.<...<<<<<<<<..<.<<<.<<<
..<......>......<<........<<<....<<..>>....>>>...<
<<<....<<<..<<<....>>>.>>>......>>>>.<<...>>.>>.<<
<....>>>.....>>>>>>>........<<<....<<<<....>>>>..>
>>..>>.>>>>>>.....<<<<<<<<.....(((.....((.>>>))...
....)))..>>>>>...>.>>>>>>..<<<((......<<<..<<<<...
...<<<<<<........<...<.<<........>>..>...>........
.......<<....>>.>>>>>>.....>>>>...>>>....<<<<<<<..
.<<...<<<<.........>>>>...>>>>>>>>..>.......<.<<<<
<..))..>>>>>.>.>>>.<<.......<<<<....>>>>.....>>..>
>>>>><<<<<.<<<<<<<...<<<.<<<<<..<<<<<<<.<<.....<<.
.......>>..........<<<<<<<.......<<.<<<..<<<<<<...
....<<..<<<<<.....>>>.......>>..>>.....<<<....>>>.
........>>>...>>>>>>>>....>>>>>>>..>>..>>>>>>>....
...<<.....>>...<....<<<<<<.......>>>>>>....>.....>
>>>>.....<<<<<<<.........>>>>>>>.....>>>...>>>>>>>
>>>.>>........<.....<<<<<<...<<<<...........<.....
..>.............>>>>..>>>>>>....>..........<<<<<<<
<<....>>>>>>>>>........
Receptor-Ligand Complex Structure
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PDB6nu3 Structural insights into unique features of the human mitochondrial ribosome recycling.
Resolution4.4 Å
Binding residue
(original residue number in PDB)		K130 K163 R166 Q312 T313 S315 L316 F317 K318 R320 R393
Binding residue
(residue number reindexed from 1)		K80 K113 R116 Q230 T231 S233 L234 F235 K236 R238 R311
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003735 structural constituent of ribosome
GO:0005515 protein binding
GO:0005525 GTP binding
Biological Process
GO:0006915 apoptotic process
GO:0032543 mitochondrial translation
GO:0097190 apoptotic signaling pathway
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005763 mitochondrial small ribosomal subunit
GO:0005840 ribosome
GO:0015935 small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6nu3, PDBe:6nu3, PDBj:6nu3
PDBsum6nu3
PubMed30962385
UniProtP51398|RT29_HUMAN Small ribosomal subunit protein mS29 (Gene Name=DAP3)

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